Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity.
about
Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.The Biochemical Cascades of the Human Pancreatic β-Cells: The Role of MicroRNAs.Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cellsChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells.SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction.Beta-Cell Injury in Ncb5or-null Mice is Exacerbated by Consumption of a High-Fat Diet.A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell deathInhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells.Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation.Integration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism.Overexpression of peroxisome proliferator-activated receptor α in pancreatic β-cells improves glucose tolerance in diet-induced obese mice.Adropin deficiency worsens HFD-induced metabolic defectsPeroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells.Inhibition of ceramide de novo synthesis reduces liver lipid accumulation in rats with nonalcoholic fatty liver disease.Effects of antidepressant drug exposure on gene expression in the developing cerebral cortex.Evidence for the involvement of GPR40 and NADPH oxidase in palmitic acid-induced superoxide production and insulin secretion.Attenuation of berberine on lipopolysaccharide-induced inflammatory and apoptosis responses in β-cells via TLR4-independent JNK/NF-κB pathway.NAD(P)H oxidase participates in the palmitate-induced superoxide production and insulin secretion by rat pancreatic islets.Identification of early biological changes in palmitate-treated isolated human islets
P2860
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P2860
Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
@zh-hant
name
Peroxisome proliferator-activa ...... on against palmitate toxicity.
@en
Peroxisome proliferator-activa ...... on against palmitate toxicity.
@nl
type
label
Peroxisome proliferator-activa ...... on against palmitate toxicity.
@en
Peroxisome proliferator-activa ...... on against palmitate toxicity.
@nl
prefLabel
Peroxisome proliferator-activa ...... on against palmitate toxicity.
@en
Peroxisome proliferator-activa ...... on against palmitate toxicity.
@nl
P2093
P2860
P1433
P1476
Peroxisome proliferator-activa ...... on against palmitate toxicity.
@en
P2093
Daniel Pipeleers
Jean-Claude Hannaert
Karen Kerckhofs
Paul Van Veldhoven
P2860
P304
P356
10.1111/J.1742-4658.2007.06131.X
P407
P577
2007-10-26T00:00:00Z