The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice - Wikidata - wikimedia - TriplyDB

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

http://www.wikidata.org/entity/Q40388321

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Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy.The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways PKC translocation and ERK1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysema Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and Disease Natriuretic Peptides in the Regulation of Cardiovascular Physiology and Metabolic Events Extracellular signal-regulated kinases 1/2 as regulators of cardiac hypertrophy Signaling effectors underlying pathologic growth and remodeling of the heart Molecular basis of physiological heart growth: fundamental concepts and new players Vascular biology of ageing-Implications in hypertension Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2)Tropomyosin de-phosphorylation in the heart: what are the consequences?Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility 17ß-Estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodeling Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice Mitogen-activated protein kinases and mitogen-activated protein kinase phosphatases mediate the inhibitory effects of all-trans retinoic acid on the hypertrophic growth of cardiomyocytes Role of protein kinase C in the signal pathways that link Na+/K+-ATPase to ERK1/2 Cardiac p300 is involved in myocyte growth with decompensated heart failure 17 beta-estradiol attenuates pressure overload-induced myocardial hypertrophy through regulating caveolin-3 protein in ovariectomized female rats Inverse regulation of preproendothelin-1 and endothelin-converting enzyme-1beta genes in cardiac cells by mechanical load O-GlcNAcylation involvement in high glucose-induced cardiac hypertrophy via ERK1/2 and cyclin D2 Distinct roles of mitogen-activated protein kinase pathways in GATA-4 transcription factor-mediated regulation of B-type natriuretic peptide gene Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice Phosphatase-coupled universal kinase assay and kinetics for first-order-rate coupling reaction ERK1/2 regulates intracellular ATP levels through alpha-enolase expression in cardiomyocytes exposed to ischemic hypoxia and reoxygenation MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors.Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction.Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy.Guanine nucleotide exchange factor-like factor (Rlf) induces gene expression and potentiates alpha 1-adrenergic receptor-induced transcriptional responses in neonatal rat ventricular myocytes.The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart.PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes.

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P2860

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

http://www.wikidata.org/entity/Q40388321

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2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年學術文章

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2000年學術文章

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2000年學術文章

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The MEK1-ERK1/2 signaling path ...... hypertrophy in transgenic mice

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The MEK1-ERK1/2 signaling path ...... hypertrophy in transgenic mice

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The MEK1-ERK1/2 signaling path ...... hypertrophy in transgenic mice

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The EMBO Journal

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The MEK1-ERK1/2 signaling path ...... hypertrophy in transgenic mice

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P2093

C F Peng

http://www.w3.org/2001/XMLSchema#string

D J Lefer

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J D Molkentin

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K M Tymitz

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L J De Windt

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O F Bueno

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R Klevitsky

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R N Kitsis

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S A Witt

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T E Hewett

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P2860

Ultrasensitivity in the mitogen-activated protein kinase cascade

Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure

Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy

Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart

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6341-6350

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10.1093/EMBOJ/19.23.6341

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23

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12225530

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11101507

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305855

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