Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy - Wikidata - wikimedia - TriplyDB

Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy

Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy

http://www.wikidata.org/entity/Q30439445

about

Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and Disease Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy Principal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart disease The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection Beta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload.Focal adhesion kinase and endothelial cell apoptosis.Integrins and integrin-associated proteins in the cardiac myocyte.A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog.Vinculin and talin: focus on the myocardium Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth FAK regulates cardiomyocyte survival following ischemia/reperfusion.Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses.Stretch-induced MAP kinase activation in cardiac myocytes: differential regulation through beta1-integrin and focal adhesion kinase Decompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets.STIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart.ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1 The costamere bridges sarcomeres to the sarcolemma in striated muscle.Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling.Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine hearts Focal adhesion kinase signaling in cardiac hypertrophy and failure.Thrombospondins in the heart: potential functions in cardiac remodeling.Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.Targeted inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis and Preserves Heart Function in Adverse Cardiac Remodeling.Mechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width.Emerging anticancer therapeutic targets and the cardiovascular system: is there cause for concern?Targeting focal adhesion kinase in fibrotic diseases.Focal adhesion signaling in heart failure The (dys)functional extracellular matrix.Focal adhesion kinase maintains, but not increases the adhesion of dental pulp cells.Effects of hydraulic pressure on cardiomyoblasts in a microfluidic device.Spatial and temporal regulation of focal adhesion kinase activity in living cells.Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injury New insights into the molecular phenotype of eccentric hypertrophy.The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.Shp shape: FAKs about hypertrophy.

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P2860

Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy

http://www.wikidata.org/entity/Q30439445

description

2006 nî lūn-bûn

@nan

2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

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2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Myocyte-restricted focal adhes ...... e overload-induced hypertrophy

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Myocyte-restricted focal adhes ...... e overload-induced hypertrophy

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type

label

Myocyte-restricted focal adhes ...... e overload-induced hypertrophy

@ast

Myocyte-restricted focal adhes ...... e overload-induced hypertrophy

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prefLabel

Myocyte-restricted focal adhes ...... e overload-induced hypertrophy

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Myocyte-restricted focal adhes ...... e overload-induced hypertrophy

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01.RES.0000240498.44752.D6

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Circulation Research

P1476

Myocyte-restricted focal adhes ...... e overload-induced hypertrophy

@en

P2093

Hilary E Beggs

http://www.w3.org/2001/XMLSchema#string

Jason T Doherty

http://www.w3.org/2001/XMLSchema#string

Laura A DiMichele

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Louis F Reichardt

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Mauricio Rojas

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P2860

The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy

Protein kinase cascades in the regulation of cardiac hypertrophy

Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy

A role for focal adhesion kinase in phenylephrine-induced hypertrophy of rat ventricular cardiomyocytes

Activation of pyk2/related focal adhesion tyrosine kinase and focal adhesion kinase in cardiac remodeling

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.

FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies

Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.

Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis

Focal adhesion kinase: the first ten years

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636-645

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scholarly article

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10.1161/01.RES.0000240498.44752.D6

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6

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99

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Christopher P Mack

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16902179

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2693055

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