Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy
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Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and DiseaseCardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathySerine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophyPrincipal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart diseaseThe smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertensionFocal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protectionBeta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload.Focal adhesion kinase and endothelial cell apoptosis.Integrins and integrin-associated proteins in the cardiac myocyte.A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog.Vinculin and talin: focus on the myocardiumTransient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growthFAK regulates cardiomyocyte survival following ischemia/reperfusion.Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignmentβ1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses.Stretch-induced MAP kinase activation in cardiac myocytes: differential regulation through beta1-integrin and focal adhesion kinaseDecompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets.STIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart.ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1The costamere bridges sarcomeres to the sarcolemma in striated muscle.Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling.Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine heartsFocal adhesion kinase signaling in cardiac hypertrophy and failure.Thrombospondins in the heart: potential functions in cardiac remodeling.Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.Targeted inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis and Preserves Heart Function in Adverse Cardiac Remodeling.Mechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width.Emerging anticancer therapeutic targets and the cardiovascular system: is there cause for concern?Targeting focal adhesion kinase in fibrotic diseases.Focal adhesion signaling in heart failureThe (dys)functional extracellular matrix.Focal adhesion kinase maintains, but not increases the adhesion of dental pulp cells.Effects of hydraulic pressure on cardiomyoblasts in a microfluidic device.Spatial and temporal regulation of focal adhesion kinase activity in living cells.Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injuryNew insights into the molecular phenotype of eccentric hypertrophy.The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.Shp shape: FAKs about hypertrophy.
P2860
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P2860
Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Myocyte-restricted focal adhes ...... e overload-induced hypertrophy
@ast
Myocyte-restricted focal adhes ...... e overload-induced hypertrophy
@en
type
label
Myocyte-restricted focal adhes ...... e overload-induced hypertrophy
@ast
Myocyte-restricted focal adhes ...... e overload-induced hypertrophy
@en
prefLabel
Myocyte-restricted focal adhes ...... e overload-induced hypertrophy
@ast
Myocyte-restricted focal adhes ...... e overload-induced hypertrophy
@en
P2093
P2860
P1433
P1476
Myocyte-restricted focal adhes ...... e overload-induced hypertrophy
@en
P2093
Hilary E Beggs
Jason T Doherty
Laura A DiMichele
Louis F Reichardt
Mauricio Rojas
P2860
P304
P356
10.1161/01.RES.0000240498.44752.D6
P577
2006-08-10T00:00:00Z