Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin. - Wikidata - wikimedia - TriplyDB

Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin.

Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin.

http://www.wikidata.org/entity/Q40389129

about

P1343

Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma Hyperforin inhibits Akt1 kinase activity and promotes caspase-mediated apoptosis involving Bad and Noxa activation in human myeloid tumor cells.Global Cell Proteome Profiling, Phospho-signaling and Quantitative Proteomics for Identification of New Biomarkers in Acute Myeloid Leukemia Patients High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemia.Can cytoplasmic nucleophosmin be detected by immunocytochemical staining of cell smears in acute myeloid leukemia?Oridonin induces NPM mutant protein translocation and apoptosis in NPM1c+ acute myeloid leukemia cells in vitro.Cytoplasmic FANCA-FANCC complex interacts and stabilizes the cytoplasm-dislocalized leukemic nucleophosmin protein (NPMc)Detection of minimal residual disease in NPM1-mutated acute myeloid leukemia by next-generation sequencing.The histone deacetylase inhibitor SAHA sensitizes acute myeloid leukemia cells to a combination of nucleoside analogs and the DNA-alkylating agent busulfan.Targeting AML through DR4 with a novel variant of rhTRAIL Cytoplasmic nucleophosmin has elevated T199 phosphorylation upon which G2/M phase progression is dependent.miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death.Nucleophosmin interacts with FOXM1 and modulates the level and localization of FOXM1 in human cancer cells.Design of FLT3 Inhibitor - Gold Nanoparticle Conjugates as Potential Therapeutic Agents for the Treatment of Acute Myeloid Leukemia.Gold nanoparticles enhance the effect of tyrosine kinase inhibitors in acute myeloid leukemia therapy.Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia Interactions of the natural product (+)-avrainvillamide with nucleophosmin and exportin-1 Mediate the cellular localization of nucleophosmin and its AML-associated mutants.Superior anti-tumor activity of the MDM2 antagonist idasanutlin and the Bcl-2 inhibitor venetoclax in p53 wild-type acute myeloid leukemia models HEXIM1, a New Player in the p53 Pathway Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia.The human nucleophosmin 1 mutation A inhibits myeloid differentiation of leukemia cells by modulating miR-10b.Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML.Nucleophosmin mutations in acute myeloid leukemia: a tale of protein unfolding and mislocalization.FOX(M1) news--it is cancer.Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression.1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1).Performance of super-SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines.A new DNA-based test for detection of nucleophosmin exon 12 mutations by capillary electrophoresis.Long noncoding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients.Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.Establishment of a quenching probe method for detection of NPM1 mutations in acute myeloid leukemia cells.Prognostic significance of NPM1 mutation-modulated microRNA-mRNA regulation in acute myeloid leukemia.MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine.DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML Down-regulated expression of NPM1 in IMS-M2 cell line by (-)-epigallocatechin-3-gallate

P2860

Q54931742-CCF8F5CC-0299-47BD-83E4-B618B2D6C8CA

P1343

Q24301836-2C46DBF9-0B72-4D08-BDE6-FC252A19E5E7 Q24652323-D14DDF74-3EAF-4A00-AC0F-89458ABDB113 Q28589317-8FC37BEE-184F-4B02-8B26-550EA213E466 Q31037798-397897B6-47D5-4CAF-9E29-6E14AA2ADF12 Q33555287-CB65B153-CFED-4B7B-AA87-EC27F2CDADFC Q33572309-AA523359-6DD0-4DDC-8024-7A4561C40DB0 Q33800539-33B61E66-73BB-4413-AEAC-B6D6D86AAC9F Q33861884-6197B1FD-4ADA-4770-887C-0B4CE6150E8B Q34333634-9DE174AF-E291-402B-BCC6-987692D12342 Q34364350-67546931-9490-4323-AA49-38DA0DCF3DE7 Q35060679-FA39FEB4-EB3C-41B3-AA61-5723292A9C6F Q35377418-F7FFA502-4EC6-4567-93CF-92E676305D60 Q35796956-135C090E-5898-4933-8CF8-00C80503C9E1 Q35837541-A990359B-DAB8-4B9A-90A9-296C2CD69A6F Q35842155-324849C7-018B-4E68-AD7E-DFC05EB04B4B Q35857472-8E2041E0-B2FF-42D4-A09C-3B38E834F598 Q35940547-526D6666-6233-415E-8107-BDFFDB9503C5 Q36206410-4EEDD4DA-2CA6-406B-9A2D-A9DDB90B423C Q36298896-87D30AF1-AFA4-4338-8E5B-E01EEBE44003 Q37045295-4EE43B50-F438-4069-94E5-F4D03BEBE99E Q37226490-EE7B4171-634E-4530-96FB-BAEDB732B91E Q37334404-F93E7D4B-034B-4269-8AA8-E24FA163C167 Q37514846-F2556365-7BF3-4E76-87D9-82B13A4C7283 Q37603441-8B613DDC-1406-47A6-B2BD-EAA64668D503 Q37687642-B9785A57-9103-4392-AA7F-A1A3DA6923E2 Q37697853-D902B748-5A9F-4E7F-BC36-9BECE4DE77FC Q38084251-9DE90E99-71F0-41B4-A32F-91F6D1C7921D Q38084903-66D21691-7BCD-4D51-A0F0-9DAFD9C28CF9 Q38245417-E4110C56-7A1A-4752-98CF-8E1A3643480E Q38262117-9EC62144-430E-4B8C-8C18-4D003402C070 Q38324384-7995F8B0-FEE7-4C06-8498-602F65B8090F Q38426552-13522666-A0B9-40B7-AE38-39458D2931F6 Q38427010-796E9131-533A-4F09-A387-B130CEE0C19A Q38698012-AD99DF38-85D7-4707-B2B3-2FAFD0E258CB Q38722849-6B08D1E7-0046-4828-AD86-06100303A8E4 Q38778620-A15AA618-1F40-4FFC-BFC4-7C36A6B90361 Q38834968-E12A615F-A977-477F-B8F7-4EF28AF06D51 Q38862452-1E42B460-5862-4CEB-A7DA-E885CA465C30 Q38947913-0008C27E-7C60-4CB8-B21B-37E671B1BDE8 Q38960308-8246295E-BDC5-4B76-99C9-2CD7A56C460A

P2860

Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin.

http://www.wikidata.org/entity/Q40389129

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh

2005年學術文章

@zh-hant

name

Cell line OCI/AML3 bears exon- ...... c expression of nucleophosmin.

@en

type

label

Cell line OCI/AML3 bears exon- ...... c expression of nucleophosmin.

@en

prefLabel

Cell line OCI/AML3 bears exon- ...... c expression of nucleophosmin.

@en

P1433

Q40389129-F0471603-0B70-4D8D-B24B-DBF1CAEC170F

P1476

Q40389129-0A38DF7A-CFAA-46E8-8403-09C4D4CA5EC7

P2093

Q40389129-3A767C42-7256-4465-9ED3-B209433496FC

Q40389129-3DABE818-80DC-4769-A635-3D836116EED3

Q40389129-58A0B0C0-E200-4762-9820-70F40A9A91B0

Q40389129-5D838822-B7B6-407E-A384-22E218D351BD

Q40389129-61F4FD14-5F14-4C0A-992F-620583424F16

Q40389129-77DB0216-4099-4B3A-BB93-0C6EEA628D7E

Q40389129-845E1409-235D-4A58-AD71-442CDCB735EC

Q40389129-A44AE644-F150-46C9-9FF0-ABDE2D214FA3

Q40389129-B05B5DCB-4A2B-4D95-9774-CE1CC1DDD4B5

Q40389129-B0A05074-7AEF-4CF5-AEF2-4D99CBDA8F3A

P2860

Q40389129-1F4ACBD8-D7AA-4E07-A879-924F11243106

Q40389129-301206C3-053C-4B0C-970C-ED7533A06BEB

Q40389129-35379C4C-91B7-4A95-9000-9346764A5F42

Q40389129-42664352-B92B-48B2-B2B4-691D164EB13A

Q40389129-42FC3324-FEF0-4B68-AD90-AD8CE0F521DF

Q40389129-43308553-27A3-4F19-AB41-8EBA15037EFB

Q40389129-60A5E898-A609-4112-9B4A-921E4522BE6A

Q40389129-6DBC8879-BC69-4954-A8E7-333F7EAB860D

Q40389129-932DA4A4-85C8-480A-9C98-B36E4F7C56DD

Q40389129-BBD49241-46D3-40D4-852D-7566E517B348

P2888

Q40389129-6910ADB0-AA6F-4FE3-B85C-8A9C0DBE868F

P304

Q40389129-E0B1A07E-882E-41E2-8770-C8D90F6D3E6D

P31

Q40389129-D04DF6E2-5718-42BC-9DEF-AF7264FC48A6

P356

Q40389129-B0A4CDD8-4B36-42EF-B8FE-1EB98E3C5AA1

P433

Q40389129-07AB3C62-EE22-42FA-8F7A-84D7057666D8

P4510

Q40389129-00B521BE-DCAE-4E74-97E1-552220546B2C

P478

Q40389129-FF07B3AC-6083-4990-BAE1-8FAE69886146

P50

Q40389129-0AE810E6-D8C8-46F9-B2A0-CE510230CF83

P577

Q40389129-BA21E4D5-A451-4D92-A917-2EE39F340F8D

P5875

Q40389129-93B6EF7B-A344-4AD4-AC53-D40BE877031F

P6179

Q40389129-EDC8613C-AA9C-48E0-8A07-F4A43CE2BEB0

P698

Q40389129-72909201-61E7-456F-AA1D-C7660078D727

P921

Q40389129-7CB100F8-7E70-4FF3-B054-F2F892F1E7FB

P356

P1433

P1476

Cell line OCI/AML3 bears exon- ...... c expression of nucleophosmin.

@en

P2093

Bigerna B

http://www.w3.org/2001/XMLSchema#string

Bolli N

http://www.w3.org/2001/XMLSchema#string

Dirks WG

http://www.w3.org/2001/XMLSchema#string

Falini B

http://www.w3.org/2001/XMLSchema#string

Liso A

http://www.w3.org/2001/XMLSchema#string

Macleod RA

http://www.w3.org/2001/XMLSchema#string

Mannucci R

http://www.w3.org/2001/XMLSchema#string

Martelli MF

http://www.w3.org/2001/XMLSchema#string

Martelli MP

http://www.w3.org/2001/XMLSchema#string

Mecucci C

http://www.w3.org/2001/XMLSchema#string

P2860

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway

Tryptophans 286 and 288 in the C-terminal region of protein B23.1 are important for its nucleolar localization

Major nucleolar proteins shuttle between nucleus and cytoplasm

Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia.

Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry.

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease.

The role of nucleophosmin in centrosome duplication.

P2888

P304

1760-1767

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.LEU.2403899

http://www.w3.org/2001/XMLSchema#string

P433

10

http://www.w3.org/2001/XMLSchema#string

P4510

P478

19

http://www.w3.org/2001/XMLSchema#string

P50

Hans Guenter Drexler

P577

2005-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7679893

http://www.w3.org/2001/XMLSchema#string

P6179

1005846018

http://www.w3.org/2001/XMLSchema#string

P698

16079892

http://www.w3.org/2001/XMLSchema#string

P921