Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells.
about
Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cellsTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneThe role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignanciesMembrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cellsMathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanismsSalinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells.Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells.CDCOCA: a statistical method to define complexity dependence of co-occuring chromosomal aberrations.Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinomaAntiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells.Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.Characterisation of the cell line HC-AFW1 derived from a pediatric hepatocellular carcinoma.WP1066 sensitizes oral squamous cell carcinoma cells to cisplatin by targeting STAT3/miR-21 axisConstitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells.STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells.Aggressive periodontitis: An appraisal of systemic effects on its etiology-genetic aspect.Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.Interleukin 37 Expression Inhibits STAT3 to Suppress the Proliferation and Invasion of Human Cervical Cancer CellsFucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway.Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer.Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomasInhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activityA novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivoTelomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancerGrowth and activation of natural killer cells ex vivo from children with neuroblastoma for adoptive cell therapy.Telomerase as a useful target in cancer fighting-the breast cancer case.Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer.p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinoma.Human telomerase expression regulation.GADD45 proteins: roles in cellular senescence and tumor development.Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3.Extending the lifespan and efficacies of immune cells used in adoptive transfer for cancer immunotherapies-A review.Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo.MiR-21 modulates hTERT through a STAT3-dependent manner on glioblastoma cell growth.Meisoindigo is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia.Hdm2 is regulated by K-Ras and mediates p53-independent functions in pancreatic cancer cells.Multistep regulation of telomerase during differentiation of HL60 cells.NFX1-123 increases hTERT expression and telomerase activity posttranscriptionally in human papillomavirus type 16 E6 keratinocytes.Nuclear factor {kappa}B-mediated transactivation of telomerase prevents intimal smooth muscle cell from replicative senescence during vascular repair.
P2860
Q21261315-7139D4D9-5327-4F3E-BB59-7621FC75501BQ26739925-D4E18733-3168-4614-BF56-DA53BE059DB9Q27008221-F3B6C468-30EF-46A2-AB33-C800207FE50DQ27309991-413686DF-42D8-4FC8-A75C-4462346D4CF4Q28539760-540FD070-AA7F-4E50-ADE1-6F9F0E4C6A4DQ33658135-25705C77-AEFE-4A52-913E-BB6B456C9BAAQ33665375-ABB59A21-9D26-46AE-9C87-1B3BD34D4C2AQ33813680-8BE286B8-6BA4-49C4-AB94-BBFC791A79C8Q33836308-35997C84-4C2F-4F82-93DD-16B732582924Q33866121-F472D3BC-3E80-45AC-B5D1-0602514FA65BQ34049230-3D0BDE83-404A-4C52-B317-C79B91C34EAEQ34069749-45B2FEF6-CA76-4980-9776-EB3C71748300Q34292958-1BCBE935-9C1E-4DED-B0BE-F9EF7A1713DCQ34719683-32252A61-93D4-491A-AAB9-211012068494Q35080781-A4766E64-EAC3-43A5-8721-918F27828FDDQ35343534-4856F0A3-2F33-4DB2-952E-4822846CFD65Q35631037-65B96029-624F-4822-82B8-95ED9B733366Q35794329-B062CECA-2156-4519-938F-C7CACBFFCC80Q35978574-9C429D6E-1573-470D-A07B-8D1C89B812F8Q36139676-137A1B04-F1EB-48A8-BCF8-908C8C52E521Q36294753-49803D40-9BAF-4FD9-B295-59A4AA656169Q36407235-E405558F-8D6D-490E-B977-121B1E91CBD0Q36622696-66D691AA-7C4D-4D51-B9AC-39EB2735B4B6Q36647747-F4E77F81-0012-49C9-BC09-934ACE77D04BQ36715258-C05A97B8-A244-45FA-8D0E-E1E829B4D5A6Q36856792-56B08130-A9A1-499A-A9F5-F23B6F5E8E98Q36868580-422F0AA6-E2AE-46D4-88E6-1613011E6643Q37371530-AAA4ECE6-2482-48DE-91C7-A7CC3AAB10F0Q37392765-CAE24853-10B1-47CD-8488-7BC5210A6311Q37905799-183D49C9-8CA8-48E4-B8D9-1547B2316D07Q38215732-E91B1EF2-92B3-4971-8B07-8794BC89CE93Q38300255-4F6233A6-4CB0-4CE2-B0F0-C74A71538C41Q38544057-92C64739-B809-4667-B921-BF4ACACC1982Q38794331-0AEFBB48-AAE9-4CFB-B7C6-B7B6454BCD45Q39329358-DF27754C-B118-4B4C-8500-BA0E944ED195Q39727094-6D3D6463-FB69-446B-8837-651C60948CF8Q39912721-2124EDE4-0832-48F3-8C01-830F50264258Q40012904-E1A7C214-45F9-465E-B905-4A39780E355AQ41358278-A62E9B15-D2B6-4BE2-9D0C-C5AC5CBEB638Q41719677-9AEDA3E6-41C0-4149-98D4-FE4BC4876187
P2860
Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Signal transducer and activato ...... uman cancer and primary cells.
@en
type
label
Signal transducer and activato ...... uman cancer and primary cells.
@en
prefLabel
Signal transducer and activato ...... uman cancer and primary cells.
@en
P2093
P1433
P1476
Signal transducer and activato ...... human cancer and primary cells
@en
P2093
Maciej Kotecki
Marina C Simeone
Matthew M Kruger
P304
P356
10.1158/0008-5472.CAN-05-0924
P407
P577
2005-08-01T00:00:00Z