Proteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasis.
about
Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPaseSemaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeletonABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells.Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cellsLong-term vector integration site analysis following retroviral mediated gene transfer to hematopoietic stem cells for the treatment of HIV infection.Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes.Sema3E/plexin-D1 mediated epithelial-to-mesenchymal transition in ovarian endometrioid cancer.Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in miceDynamics of the skeletal muscle secretome during myoblast differentiation.Diverse functions for the semaphorin receptor PlexinD1 in development and disease.Effect of C-terminal sequence on competitive semaphorin binding to neuropilin-1The semaphorins.Semaphorins in angiogenesis and tumor progression.Exploiting pleiotropic activities of semaphorins as multi-target therapies for cancerTumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform.The role of semaphorins and their receptors in gliomasEpigenetically downregulated Semaphorin 3E contributes to gastric cancerExpression of semaphorin 3A and neuropilin 1 with clinicopathological features and survival in human tongue cancer.Migration-promoting role of VEGF-C and VEGF-C binding receptors in human breast cancer cells.The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironmentSemaphorins and their receptors in lung cancer.Neuropilins: novel targets for anti-angiogenesis therapies.Enhanced expression of semaphorin 3E is involved in the gastric cancer development.Gating of Sema3E/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development.Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models.Semaphorin signals on the road to cancer invasion and metastasis.Overexpression of Semaphorin-3E enhances pancreatic cancer cell growth and associates with poor patient survivalThe role and mechanism-of-action of Sema3E and Plexin-D1 in vascular and neural development.The role of semaphorins and their receptors in vascular development and cancer.Neuropilins: a new target for cancer therapy.Semaphorin receptors meet receptor tyrosine kinases on the way of tumor progression.The emerging role of class-3 semaphorins and their neuropilin receptors in oncology.The potential of class 3 semaphorins as both targets and therapeutics in cancer.Semaphorins and Their Roles in Airway Biology: Potential as Therapeutic Targets.The role of the semaphorins in cancer.The proprotein convertase furin in tumour progression.A role for class 3 semaphorins in prostate cancer.Role of the nervous system in cancer metastasis.Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin
P2860
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P2860
Proteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Proteolytic processing convert ...... ve growth and lung metastasis.
@en
type
label
Proteolytic processing convert ...... ve growth and lung metastasis.
@en
prefLabel
Proteolytic processing convert ...... ve growth and lung metastasis.
@en
P2093
P50
P1433
P1476
Proteolytic processing convert ...... ve growth and lung metastasis.
@en
P2093
Birthe Thomsen
Claus Christensen
Eugene Lukanidin
Noona Ambartsumian
Per Guldberg
P304
P356
10.1158/0008-5472.CAN-04-4309
P407
P577
2005-07-01T00:00:00Z