Functional cartography of the ectodomain of the type I interferon receptor subunit ifnar1.
about
Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingStructural Linkage between Ligand Discrimination and Receptor Activation by Type I InterferonsStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1Live cell micropatterning reveals the dynamics of signaling complexes at the plasma membraneIFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosusFundamental aspects of protein-protein association kineticsDetermination of the two-dimensional interaction rate constants of a cytokine receptor complex.The differential antiviral activities of chicken interferon α (ChIFN-α) and ChIFN-β are related to distinct interferon-stimulated gene expression.Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-α receptor 1 antibodyA fully human monoclonal antibody with novel binding epitope and excellent neutralizing activity to multiple human IFN-α subtypes: A candidate therapy for systemic lupus erythematosus.Binding of interferon reduces the force of unfolding for interferon receptor 1.Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells.Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta.A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.Homo-oligomerization of the activating natural killer cell receptor NKp30 ectodomain increases its binding affinity for cellular ligands.The molecular basis for differential type I interferon signaling.NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site.Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1.Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.The EM structure of a type I interferon-receptor complex reveals a novel mechanism for cytokine signaling.A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans.Biological roles of interferon tau (IFNT) and type I IFN receptors in elongation of the ovine conceptus.
P2860
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P2860
Functional cartography of the ectodomain of the type I interferon receptor subunit ifnar1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Functional cartography of the ...... feron receptor subunit ifnar1.
@en
type
label
Functional cartography of the ...... feron receptor subunit ifnar1.
@en
prefLabel
Functional cartography of the ...... feron receptor subunit ifnar1.
@en
P2093
P1476
Functional cartography of the ectodomain of the type I interferon receptor subunit ifnar1
@en
P2093
Imke Peters
Jacob Piehler
José Van der Heyden
Martynas Gavutis
Peter Lamken
P304
P356
10.1016/J.JMB.2005.05.008
P407
P50
P577
2005-07-01T00:00:00Z