A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
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Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillationGain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillationMutations in sodium channel β1- and β2-subunits associated with atrial fibrillationNeuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and PitfallsIon Channels in the HeartEmerging directions in the genetics of atrial fibrillationIon channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathMicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillationKv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillationLosartan prevents stretch-induced electrical remodeling in cultured atrial neonatal myocytesNovel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillationChloroquine terminates stretch-induced atrial fibrillation more effectively than flecainide in the sheep heartA KCNQ1 mutation causes a high penetrance for familial atrial fibrillation.Potassium channel gene mutations rarely cause atrial fibrillationSingle nucleotide polymorphisms in proximity to K-channel genes are associated with decreased longitudinal QTc variance.A contemporary review on the genetic basis of atrial fibrillation.The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel.PITX2-dependent gene regulation in atrial fibrillation and rhythm control.Genetic variants related to height and risk of atrial fibrillation: the cardiovascular health studyAtrial fibrillation in congestive heart failure.Genetics of atrial fibrillationEvaluation of non-synonymous NPPA single nucleotide polymorphisms in atrial fibrillationEmerging concepts in the pharmacogenomics of arrhythmias: ion channel trafficking.Regulation of cardiac inward rectifier potassium current (I(K1)) by synapse-associated protein-97.Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity.Personalized medicine and atrial fibrillation: will it ever happen?Monogenic atrial fibrillation as pathophysiological paradigms.Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.Atrial Fibrillation and SCN5A Variants.KCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia.Genetics of atrial fibrillation: implications for future research directions and personalized medicine.Primary periodic paralyses.Examining rare and low-frequency genetic variants previously associated with lone or familial forms of atrial fibrillation in an electronic medical record system: a cautionary note.Left atrial transcriptional changes associated with atrial fibrillation susceptibility and persistenceGenetics of atrial fibrillation and possible implications for ischemic stroke.Recent advances in the molecular pathophysiology of atrial fibrillation.Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 and the Ras/MAPK pathway.Atrial fibrillation: current knowledge and future directions in epidemiology and genomics.Genetic Analysis of Arrhythmogenic Diseases in the Era of NGS: The Complexity of Clinical Decision-Making in Brugada Syndrome.
P2860
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P2860
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
@en
type
label
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
@en
prefLabel
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
@en
P2093
P1476
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.
@en
P2093
Haiying Wan
Jacques Barhanin
Marie-Madeleine Larroque
Petra Eurlings
P304
P356
10.1016/J.BBRC.2005.05.054
P577
2005-07-01T00:00:00Z