Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis. - Wikidata - wikimedia - TriplyDB

Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

http://www.wikidata.org/entity/Q40417128

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The enigma of caspase-2: the laymen's view High-throughput screening to enhance oncolytic virus immunotherapy Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.Activation of Bak in ultrasound-induced, JNK- and p38-independent apoptosis and its inhibition by Bcl-2 p23/Tmp21 associates with protein kinase Cdelta (PKCdelta) and modulates its apoptotic function.Caspase-2 promotes cytoskeleton protein degradation during apoptotic cell death.Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim.A nonapoptotic role for CASP2/caspase 2: modulation of autophagy.Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.Metabolic control of oocyte apoptosis mediated by 14-3-3zeta-regulated dephosphorylation of caspase-2 Differential cardiotoxic/cardioprotective effects of beta-adrenergic receptor subtypes in myocytes and fibroblasts in doxorubicin cardiomyopathy.Combined effect of papuamine and doxorubicin in human breast cancer MCF-7 cells.Baicalein protects against doxorubicin-induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation.β2-adrenergic receptors mediate cardioprotection through crosstalk with mitochondrial cell death pathways.α2β1 integrin promotes chemoresistance against doxorubicin in cancer cells through extracellular signal-regulated kinase (ERK).Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15.A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro Enhanced apoptosis of ovarian cancer cells via nanocarrier-mediated codelivery of siRNA and doxorubicin.Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice.Phosphorylation of IκBα at serine 32 by T-lymphokine-activated killer cell-originated protein kinase is essential for chemoresistance against doxorubicin in cervical cancer cells.Transcription of the protein kinase C-delta gene is activated by JNK through c-Jun and ATF2 in response to the anticancer agent doxorubicin.Protein kinase C signalling in leukemia.The role of caspase-2 in stress-induced apoptosis.Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.Caspases and kinases in a death grip.Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate.Protein kinase cδ in apoptosis: a brief overview.Compartmentalization of the foregut tube: developmental origins of the trachea and esophagus.Doxorubicin-induced death in tumour cells and cardiomyocytes: is autophagy the key to improving future clinical outcomes?The Multifunctions of WD40 Proteins in Genome Integrity and Cell Cycle Progression.Protective effect of oleanolic acid on oxidative injury and cellular abnormalities in doxorubicin induced cardiac toxicity in rats.Anticancer activity of salicin and fenofibrate.Ellagic acid induces novel and atypical PKC isoforms and promotes caspase-3 dependent apoptosis by blocking energy metabolism.Co-administration phenoxodiol with doxorubicin synergistically inhibit the activity of sphingosine kinase-1 (SphK1), a potential oncogene of osteosarcoma, to suppress osteosarcoma cell growth both in vivo and in vitro.5-Phenylselenyl- and 5-methylselenyl-methyl-2'-deoxyuridine induce oxidative stress, DNA damage, and caspase-2-dependent apoptosis in cancer cells.Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines.Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL.Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells.Etoposide induces protein kinase Cdelta- and caspase-3-dependent apoptosis in neuroblastoma cancer cells.

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Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

http://www.wikidata.org/entity/Q40417128

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2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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Doxorubicin requires the seque ...... al kinase to induce apoptosis.

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Doxorubicin requires the seque ...... al kinase to induce apoptosis.

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Doxorubicin requires the seque ...... al kinase to induce apoptosis.

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MBC.E04-10-0862

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Molecular Biology of the Cell

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Doxorubicin requires the seque ...... nal kinase to induce apoptosis

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P2093

Ann-Charlotte Björklund

http://www.w3.org/2001/XMLSchema#string

Aristidis Moustakas

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Dan Grandér

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Edward Laane

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Maria C Shoshan

http://www.w3.org/2001/XMLSchema#string

Mats Heyman

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P2860

Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3

Transcription factor ATF2 regulation by the JNK signal transduction pathway

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis

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3821-3831

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scholarly article

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10.1091/MBC.E04-10-0862

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8

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16

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Boris Zhivotovsky

Theocharis Panaretakis

Katja Pokrovskaja Tamm

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2005-05-25T00:00:00Z

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15917298

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1182319

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