Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination. - Wikidata - wikimedia - TriplyDB

Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

http://www.wikidata.org/entity/Q34748645

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The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility The chick embryo as an expanding experimental model for cancer and cardiovascular research Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1.Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration P2X(7) receptor antagonists display agonist-like effects on cell signaling proteins.Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells.Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734 Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase.The emergence of extracellular vesicles in urology: fertility, cancer, biomarkers and targeted pharmacotherapy.The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3 Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis.Cell surface remodeling by plasmin: a new function for an old enzyme.New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.The origin of prostate metastases: emerging insights.Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy.In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling Infrared spectral signatures of CDCP1-induced effects in colon carcinoma cells.Evaluation of metastatic and angiogenic potentials of human colon carcinoma cells in chick embryo model systems.Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer.Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration.Cub domain containing protein 1 (CDCP1) negatively regulates TGFβ signaling and myofibroblast differentiation.

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Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

http://www.wikidata.org/entity/Q34748645

description

2009 nî lūn-bûn

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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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Functional role of cell surfac ...... 1 in tumor cell dissemination.

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1541-7786.MCR-09-0100

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Molecular Cancer Research

P1476

Functional role of cell surfac ...... 1 in tumor cell dissemination

@en

P2093

Andreas Wortmann

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Elena I Deryugina

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Erin M Conn

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James P Quigley

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Juneth J Partridge

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Tatyana A Kupriyanova

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Veronica C Ardi

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P2860

Adhesion signaling by a novel mitotic substrate of src kinases

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma

Apoptosis: controlled demolition at the cellular level

The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151.

Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer.

The C2 domain of PKCdelta is a phosphotyrosine binding domain.

Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia.

Single-chain antibody-based gene therapy: inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell-associated matrices.

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

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1197-1211

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scholarly article

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10.1158/1541-7786.MCR-09-0100

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8

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7

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2009-08-11T00:00:00Z

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19671673

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3068911

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