Selective inhibition of alpha1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop. - Wikidata - wikimedia - TriplyDB

Selective inhibition of alpha1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop.

Selective inhibition of alpha1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop.

http://www.wikidata.org/entity/Q40417203

about

Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome Abundance and stability of complexes containing inactive G protein-coupled receptors and G proteins Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13 Deregulation of RGS2 in cardiovascular diseases Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gαq Complex Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction The RGS2 (-391, C>G) genetic variation correlates to antihypertensive drug responses in Chinese patients with essential hypertension RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Structure of the Regulator of G Protein Signaling 8 (RGS8)-Gαq Complex: MOLECULAR BASIS FOR Gα SELECTIVITY.The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality.RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling.Novel peptide ligands of RGS4 from a focused one-bead, one-compound library.Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis The α1-adrenergic receptors: diversity of signaling networks and regulation Regulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells.How regulators of G protein signaling achieve selective regulation.Protein-protein interactions at the adrenergic receptors.A finer tuning of G-protein signaling through regulated control of RGS proteins.Recent progress in alpha1-adrenergic receptor research.R4 RGS proteins: regulation of G-protein signaling and beyond.Modulation of receptor dynamics by the regulator of G protein signaling Sst2.A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors A physiologically required G protein-coupled receptor (GPCR)-regulator of G protein signaling (RGS) interaction that compartmentalizes RGS activity.Mu opioid receptor activation enhances regulator of G protein signaling 4 association with the mu opioid receptor/G protein complex in a GTP-dependent manner.Fine-tuning of GPCR activity by receptor-interacting proteins Structure, function, and localization of Gβ5-RGS complexes.Cardiac and neuroprotection regulated by α(1)-adrenergic receptor subtypes RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells.Unique hydrophobic extension of the RGS2 amphipathic helix domain imparts increased plasma membrane binding and function relative to other RGS R4/B subfamily members.RGS2 inhibits the epithelial Ca2+ channel TRPV6.Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity.Mutational analysis of predicted intracellular loop domains of human motilin receptor.Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins Regulation of RGS2 and Second Messenger Signaling in Vascular Smooth Muscle Cells by cGMP-dependent Protein Kinase

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P2860

Selective inhibition of alpha1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop.

http://www.wikidata.org/entity/Q40417203

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

@zh-my

2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Selective inhibition of alpha1 ...... ptor third intracellular loop.

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type

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Selective inhibition of alpha1 ...... ptor third intracellular loop.

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prefLabel

Selective inhibition of alpha1 ...... ptor third intracellular loop.

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Journal of Biological Chemistry

P1476

Selective inhibition of alpha1 ...... ptor third intracellular loop.

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P2093

Chris Hague

http://www.w3.org/2001/XMLSchema#string

John R Hepler

http://www.w3.org/2001/XMLSchema#string

Kenneth P Minneman

http://www.w3.org/2001/XMLSchema#string

Leah S Bernstein

http://www.w3.org/2001/XMLSchema#string

Suneela Ramineni

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Zhongjian Chen

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P2860

Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs

Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain

The aorta and heart differentially express RGS (regulators of G-protein signalling) proteins that selectively regulate sphingosine 1-phosphate, angiotensin II and endothelin-1 signalling

RGS2/G0S8 is a selective inhibitor of Gqalpha function

Mechanisms governing subcellular localization and function of human RGS2

A comparison of aorta and vena cava medial message expression by cDNA array analysis identifies a set of 68 consistently differentially expressed genes, all in aortic media

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

The regulator of G protein signaling family

Evidence for a short form of RGS3 preferentially expressed in the human heart

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27289-27295

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scholarly article

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10.1074/JBC.M502365200

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29

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280

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15917235

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