The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies.
about
Glucuronidation of 3'-azido-3'-deoxythymidine (zidovudine) by human liver microsomes: relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acid.Identification of In Vitro Metabolites of Amoxicillin in Human Liver Microsomes by LC-ESI/MS.Combination of a MDR1-targeted replicative adenovirus and chemotherapy for the therapy of pretreated ovarian cancer.Assessment of drug-drug interactions: concepts and approaches.Optimization of metabolic stability as a goal of modern drug design.Strategies to assess the drug interaction potential in translational medicine.An evaluation of the latest in vitro tools for drug metabolism studies.Drug Metabolism in Preclinical Drug Development: A Survey of the Discovery Process, Toxicology, and Computational Tools.Considerations in the design of toxicokinetic programs.Past, present, and future applications of precision-cut liver slices for in vitro xenobiotic metabolism.The human drug metabolizing cytochromes P450.Effect of Water Miscible Organic Solvents on p-Nitrophenol Hydroxylase (CYP2E1) Activity in Rat Liver MicrosomesIn vitro and in vivo studies to characterize the clearance mechanism and potential cytochrome P450 interactions of anidulafungin.Characterization of in vitro metabolites of TM-2, a potential antitumor drug, in rat, dog and human liver microsomes using liquid chromatography/tandem mass spectrometry.Use of precision-cut rat liver slices for studies of xenobiotic metabolism and toxicity: comparison of the Krumdieck and Brendel tissue slicers.Cytochrome P450 enzyme activity and protein expression in primary porcine enterocyte and hepatocyte cultures.In Vitro Drug Metabolism Using Liver Microsomes.
P2860
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P2860
The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
The use of in vitro metabolism ...... tation of drug safety studies.
@en
type
label
The use of in vitro metabolism ...... tation of drug safety studies.
@en
prefLabel
The use of in vitro metabolism ...... tation of drug safety studies.
@en
P2093
P2860
P1476
The use of in vitro metabolism ...... tation of drug safety studies.
@en
P2093
M VandenBranden
S A Wrighton
P2860
P304
P356
10.1177/019262339502300214
P407
P577
1995-03-01T00:00:00Z