Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily
about
Genomic organization of Tropomodulins 2 and 4 and unusual intergenic and intraexonic splicing of YL-1 and Tropomodulin 4Cytochrome P4502C9: an enzyme of major importance in human drug metabolismGene structure of CYP2C8 and extrahepatic distribution of the human CYP2CsEstablishment of a transgenic cell line stably expressing human cytochrome P450 2C18 and identification of a CYP2C18 clone with exon 5 missingInterethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individualsMolecular genetics of the human cytochrome P450 monooxygenase superfamilyGenetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity.Structural and functional studies of UDP-glucuronosyltransferases.Clinical application of pharmacogenomics.Proguanil metabolism is determined by the mephenytoin oxidation polymorphism in Vietnamese living in Denmark.Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolismIn vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase.A study of the interaction between omeprazole and cyclosporine in renal transplant patients.Bench to bedside: Pharmacogenomics, adverse drug interactions, and the cytochrome P450 system.RNA molecules containing exons originating from different members of the cytochrome P450 2C gene subfamily (CYP2C) in human epidermis and liverHuman cytochromes P450: evolution and cDNA-directed expression.PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19.A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients.The human hepatic cytochromes P450 involved in drug metabolism.Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19.Cloning of cytochrome P-450 2C9 cDNA from human liver and its expression in CHL cells.The human intestinal cytochrome P450 "pie".Sex-specific differences in CYP450 isoforms in humans.In vitro cytochrome p450 formation of a mono-hydroxylated metabolite of zearalenone exhibiting estrogenic activities: possible occurrence of this metabolite in vivo.Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues.CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects.Genetic polymorphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China.The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies.Pharmacogenetics in clinical pharmacology and toxicology.P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer.In vitro methods for assessing human hepatic drug metabolism: their use in drug development.In vitro assessment of human cytochrome P450.Phenytoin disposition and toxicity: role of pharmacogenetic and interethnic factors.Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily.Homology modeling and substrate binding study of human CYP2C18 and CYP2C19 enzymes.Baculovirus-mediated expression of cytochrome P4502C8 and human NADPH-cytochrome P450 reductase: optimization of protein expression.Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes.Frequency of selected single nucleotide polymorphisms influencing the warfarin pharmacogenetics in Slovak population.Photoaffinity labeling probe for the substrate binding site of human phenol sulfotransferase (SULT1A1): 7-azido-4-methylcoumarin.Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.
P2860
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P2860
Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily
description
1991 nî lūn-bûn
@nan
1991 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
name
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@ast
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@en
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@nl
type
label
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@ast
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@en
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@nl
prefLabel
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@ast
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@en
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@nl
P2093
P356
P1433
P1476
Cloning and expression of comp ...... n cytochrome P450IIC subfamily
@en
P2093
J A Blaisdell
J A Goldstein
M B Faletto
P304
P356
10.1021/BI00227A012
P407
P577
1991-04-02T00:00:00Z