Stage-specific repression by the EKLF transcriptional activator.
about
Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)Mammalian Krüppel-like factors in health and diseasesSolution Structure of the mSin3A PAH2–Pf1 SID1 Complex: A Mad1/Mxd1-Like Interaction Disrupted by MRG15 in the Rpd3S/Sin3S ComplexThe erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stabilityEKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiationTranscription factor EKLF (KLF1) recruitment of the histone chaperone HIRA is essential for β-globin gene expression.Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor EklfGeneration of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencingTranscriptional control of erythropoiesis: emerging mechanisms and principles.Alterations in expression and chromatin configuration of the alpha hemoglobin-stabilizing protein gene in erythroid Kruppel-like factor-deficient mice.Lineage-specific activators affect beta-globin locus chromatin in multipotent hematopoietic progenitors.Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3).Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation.Nonhistone protein acetylation as cancer therapy targets.The multifunctional role of EKLF/KLF1 during erythropoiesis.Foxo3 is required for the regulation of oxidative stress in erythropoiesis.Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2CβRegulation of human fetal hemoglobin: new players, new complexities.Solution NMR studies of apo-mSin3A and -mSin3B reveal that the PAH1 and PAH2 domains are structurally independent.Tissue-restricted transcription from a conserved intragenic CpG island in the Klf1 gene in mice.Novel roles for KLF1 in erythropoiesis revealed by mRNA-seq.Advances in the understanding of haemoglobin switching.EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination.Orchestration of late events in erythropoiesis by KLF1/EKLF.Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus.Non-random subcellular distribution of variant EKLF in erythroid cells.Sumoylation of EKLF promotes transcriptional repression and is involved in inhibition of megakaryopoiesis.Novel role for EKLF in megakaryocyte lineage commitment.Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator-activated receptor γ (PPARγ) during adipocyte differentiation.Histone deacetylase 1 activates PU.1 gene transcription through regulating TAF9 deacetylation and transcription factor IID assembly.EKLF/KLF1 is ubiquitinated in vivo and its stability is regulated by activation domain sequences through the 26S proteasome.Survey and evaluation of mutations in the human KLF1 transcription unit.6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells.Krüppel-like factors: Crippling and un-crippling metabolic pathways.
P2860
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P2860
Stage-specific repression by the EKLF transcriptional activator.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Stage-specific repression by the EKLF transcriptional activator.
@en
type
label
Stage-specific repression by the EKLF transcriptional activator.
@en
prefLabel
Stage-specific repression by the EKLF transcriptional activator.
@en
P2860
P1476
Stage-specific repression by the EKLF transcriptional activator.
@en
P2093
James J Bieker
Xiaoyong Chen
P2860
P304
10416-10424
P356
10.1128/MCB.24.23.10416-10424.2004
P407
P577
2004-12-01T00:00:00Z