The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration.
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Role of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cellsSphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential RisksEmerging role of sphingosine-1-phosphate signaling in head and neck squamous cell carcinomaS1PR2 links germinal center confinement and growth regulationG Protein-Coupled Receptor Signaling in Stem Cells and CancerSphingolipid signaling in metabolic disordersFingolimod for the treatment of neurological diseases-state of play and future perspectivesHDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 productionReceptor-mediated vascular smooth muscle migration induced by LPA involves p38 mitogen-activated protein kinase pathway activationS1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumorInduction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line.GPCRs and cancerS1P metabolism in cancer and other pathological conditions.Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2.Extracellular and intracellular actions of sphingosine-1-phosphateSphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient miceSphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degenerationInhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation.Regulation of cancer cell migration and invasion by sphingosine-1-phosphateSphingosine-1-phosphate receptor 2Sphingosine-1-phosphate promotes extravillous trophoblast cell invasion by activating MEK/ERK/MMP-2 signaling pathways via S1P/S1PR1 axis activationTumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind HydeLipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatmentAntitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma.Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness.Molecular pathways triggering glioma cell invasion.ROCK1 mediates leukocyte recruitment and neointima formation following vascular injuryThe therapeutic effects of Rho-ROCK inhibitors on CNS disorders.Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα12/13-Rho-Rac1 pathwaySphingosine-1-phosphate and interleukin-1 independently regulate plasminogen activator inhibitor-1 and urokinase-type plasminogen activator receptor expression in glioblastoma cells: implications for invasivenessPotential signaling pathway involved in sphingosine-1-phosphate-induced epithelial-mesenchymal transition in cancer.Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature.Regulation and functions of sphingosine kinases in the brainSphingosine 1-phosphate receptors are essential mediators of eyelid closure during embryonic developmentTargeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts.Regulation of vascular physiology and pathology by the S1P2 receptor subtype.Site-specific metastasis formation: chemokines as regulators of tumor cell adhesion, motility and invasion.Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop
P2860
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P2860
The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The G protein-coupled receptor ...... inhibit tumor cell migration.
@en
type
label
The G protein-coupled receptor ...... inhibit tumor cell migration.
@en
prefLabel
The G protein-coupled receptor ...... inhibit tumor cell migration.
@en
P2093
P1433
P1476
The G protein-coupled receptor ...... inhibit tumor cell migration.
@en
P2093
Denise Lepley
Fernando Ferrer
Ji-Hye Paik
P304
P356
10.1158/0008-5472.CAN-04-2311
P407
P50
P577
2005-05-01T00:00:00Z