Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase.
about
Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2Productive parvovirus B19 infection of primary human erythroid progenitor cells at hypoxia is regulated by STAT5A and MEK signaling but not HIFαHypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathwayMolecular Pathways: Targeting Diacylglycerol Kinase Alpha in CancerDiacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.Rapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2.The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src.Updated and new perspectives on diagnosis, prognosis, and therapy of malignant pheochromocytoma/paraganglioma.Transcription association of VHL and SDH mutations link hypoxia and oxidoreductase signals in pheochromocytomas.Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?miR-17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia-Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation.Changing paradigms in the treatment of malignant pheochromocytoma.HIF-prolyl hydroxylases and cardiovascular diseases.Dysregulated pH in Tumor Microenvironment Checkmates Cancer Therapy.Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).Prolyl hydroxylase mediated inhibition of fatty acid synthase to combat tumor growth in mammary gland carcinoma.Discovery of a murine model of clinical PAH: Mission impossible?Angiogenic growth factors augment K-Cl cotransporter expression in erythroid cells via hypoxia-inducible factor-1α.Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signalings.Diacylglycerol kinase (DGK) inhibitor II (R59949) could suppress retinal neovascularization and protect retinal astrocytes in an oxygen-induced retinopathy model.
P2860
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P2860
Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Activation of HIF-prolyl hydro ...... of the diacylglycerol kinase.
@en
type
label
Activation of HIF-prolyl hydro ...... of the diacylglycerol kinase.
@en
prefLabel
Activation of HIF-prolyl hydro ...... of the diacylglycerol kinase.
@en
P2093
P2860
P50
P356
P1476
Activation of HIF-prolyl hydro ...... r of the diacylglycerol kinase
@en
P2093
Elisa Temes
Gemma Olmos
Manuel O Landazuri
Maria C Castellanos
Mónica Feijoo-Cuaresma
P2860
P304
24238-24244
P356
10.1074/JBC.M414694200
P407
P577
2005-04-23T00:00:00Z