Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase. - Wikidata - wikimedia - TriplyDB

Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase.

Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase.

http://www.wikidata.org/entity/Q40431257

about

Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2 Productive parvovirus B19 infection of primary human erythroid progenitor cells at hypoxia is regulated by STAT5A and MEK signaling but not HIFα Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway Molecular Pathways: Targeting Diacylglycerol Kinase Alpha in Cancer Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.Rapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2.The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src.Updated and new perspectives on diagnosis, prognosis, and therapy of malignant pheochromocytoma/paraganglioma.Transcription association of VHL and SDH mutations link hypoxia and oxidoreductase signals in pheochromocytomas.Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?miR-17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia-Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation.Changing paradigms in the treatment of malignant pheochromocytoma.HIF-prolyl hydroxylases and cardiovascular diseases.Dysregulated pH in Tumor Microenvironment Checkmates Cancer Therapy.Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).Prolyl hydroxylase mediated inhibition of fatty acid synthase to combat tumor growth in mammary gland carcinoma.Discovery of a murine model of clinical PAH: Mission impossible?Angiogenic growth factors augment K-Cl cotransporter expression in erythroid cells via hypoxia-inducible factor-1α.Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signalings.Diacylglycerol kinase (DGK) inhibitor II (R59949) could suppress retinal neovascularization and protect retinal astrocytes in an oxygen-induced retinopathy model.

P2860

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P2860

Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase.

http://www.wikidata.org/entity/Q40431257

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Activation of HIF-prolyl hydro ...... of the diacylglycerol kinase.

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type

label

Activation of HIF-prolyl hydro ...... of the diacylglycerol kinase.

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Activation of HIF-prolyl hydro ...... of the diacylglycerol kinase.

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P1433

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P1476

Activation of HIF-prolyl hydro ...... r of the diacylglycerol kinase

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P2093

Elisa Temes

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Gemma Olmos

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Manuel O Landazuri

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Maria C Castellanos

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Mónica Feijoo-Cuaresma

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P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

A conserved family of prolyl-4-hydroxylases that modify HIF

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Phospholipase D: molecular and cell biology of a novel gene family

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24238-24244

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10.1074/JBC.M414694200

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280

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Silvia Martin-Puig

Barbara Acosta-Iborra

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2005-04-23T00:00:00Z

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15849364

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