Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.
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Cited2, a coactivator of HNF4alpha, is essential for liver developmentA Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase geneDual promoters control the cell-specific expression of the human cell death-inducing DFF45-like effector B geneTRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.Distinct modes of regulation of transcription of hepatitis B virus by the nuclear receptors HNF4alpha and COUP-TF1Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementationPredictive screening for regulators of conserved functional gene modules (gene batteries) in mammals.Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsA developmental transition in definitive erythropoiesis: erythropoietin expression is sequentially regulated by retinoic acid receptors and HNF4Plasticity and expanding complexity of the hepatic transcription factor network during liver developmentGATA6 is essential for embryonic development of the liver but dispensable for early heart formationBerberine Attenuates Development of the Hepatic Gluconeogenesis and Lipid Metabolism Disorder in Type 2 Diabetic Mice and in Palmitate-Incubated HepG2 Cells through Suppression of the HNF-4α miR122 PathwayThe nuclear receptor hepatocyte nuclear factor 4alpha acts as a morphogen to induce the formation of microvilliHepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasisThe hepatitis E virus ORF3 protein regulates the expression of liver-specific genes by modulating localization of hepatocyte nuclear factor 4Hepatocyte nuclear factor (HNF)-4alpha induces expression of endothelial Fas ligand (FasL) to prevent cancer cell transmigration: a novel defense mechanism of endothelium against cancer metastasis.Bisphenol A Disrupts HNF4α-Regulated Gene Networks Linking to Prostate Preneoplasia and Immune Disruption in Noble Rats.Lessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism.A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cellsGeneration of mice harbouring a conditional loss-of-function allele of Gata6.Molecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregatesContribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells.Mitochondrial metabolism and diabetesHepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.Hepatocyte nuclear factor-4alpha induces transdifferentiation of hematopoietic cells into hepatocytesGATA4 is essential for jejunal function in miceHepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytesHepatocyte nuclear factor 4α (HNF4α) in coordination with retinoic acid receptors increases all-trans-retinoic acid-dependent CYP26A1 gene expression in HepG2 human hepatocytes.Embryonic stem cells develop into hepatocytes after intrasplenic transplantation in CCl4-treated miceA new FACS approach isolates hESC derived endoderm using transcription factors.Critical roles of nuclear receptor response elements in replication of hepatitis B virus.Dissecting the transcriptional network of pancreatic islets during development and differentiation.A transcription factor regulatory circuit in differentiated pancreatic cells.Inhibitor of the tissue-specific transcription factor HNF4, a potential regulator in early Xenopus development.Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems.Dynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life.Transforming growth factor-β1 suppresses hepatitis B virus replication by the reduction of hepatocyte nuclear factor-4α expression.Beta-catenin signaling in hepatic development and progenitors: which way does the WNT blow?The existence of multipotent stem cells with epithelial-mesenchymal transition features in the human liver bud.Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alpha
P2860
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P2860
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-my
2000年学术文章
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2000年學術文章
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2000年學術文章
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2000年學術文章
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name
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.
@en
type
label
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.
@en
prefLabel
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.
@en
P2860
P1433
P1476
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
@en
P2860
P304
P577
2000-02-01T00:00:00Z