Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset.
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Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controlsGenetics of type 1 diabetesPredominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium familiesNext generation sequencing reveals the association of DRB3*02:02 with type 1 diabetes.HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics ConsortiumAssociation analysis of SNPs in the IL4R locus with type I diabetes.The type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes.Evidence for association of the TCF7 locus with type I diabetes.Genetic variation within the HLA class III influences T1D susceptibility conferred by high-risk HLA haplotypes.Screen and clean: a tool for identifying interactions in genome-wide association studiesConditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHCRelative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis.Extreme genetic risk for type 1A diabetesThe HLA-B 3906 allele imparts a high risk of diabetes only on specific HLA-DR/DQ haplotypes.Dominant suppression of Addison's disease associated with HLA-B15Emerging applications of metabolomic and genomic profiling in diabetic clinical medicine.Genetics of the HLA region in the prediction of type 1 diabetes.Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians.Replication and further characterization of a Type 1 diabetes-associated locus at the telomeric end of the major histocompatibility complexExtreme genetic risk for type 1A diabetes in the post-genome eraLinkage disequilibrium with predisposing DR3 haplotypes accounts for apparent effects of tumor necrosis factor and lymphotoxin-alpha polymorphisms on type 1 diabetes susceptibilityUse of class I and class II HLA loci for predicting age at onset of type 1 diabetes in multiple populations.HLA class I and II alleles are associated with microvascular complications of type 1 diabetes.Primer: immunity and autoimmunityAnalysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetesDefining multiple common "completely" conserved major histocompatibility complex SNP haplotypesFrom markers to molecular mechanisms: type 1 diabetes in the post-GWAS era.Type 1 diabetes in the BB rat: a polygenic diseaseLocalization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-AConfirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A.In antibody-positive first-degree relatives of patients with type 1 diabetes, HLA-A*24 and HLA-B*18, but not HLA-B*39, are predictors of impending diabetes with distinct HLA-DQ interactions.Type 1 diabetes: etiology, immunology, and therapeutic strategies.The past, present, and future of genetic associations in type 1 diabetes.Does familial clustering of risk factors for long-term diabetic complications leave any place for genes that act independently?Influence of type 1 diabetes genes on disease progression: similarities and differences between countries.Identification and characterisation of peptide binding motifs of six autoimmune disease-associated human leukocyte antigen-class I molecules including HLA-B*39:06.Accommodating linkage disequilibrium in genetic-association analyses via ridge regression.The HLA Region and Autoimmune Disease: Associations and Mechanisms of Action.
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P2860
Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Human leukocyte antigen class ...... tibility and age at T1D onset.
@en
type
label
Human leukocyte antigen class ...... tibility and age at T1D onset.
@en
prefLabel
Human leukocyte antigen class ...... tibility and age at T1D onset.
@en
P2860
P1433
P1476
Human leukocyte antigen class ...... tibility and age at T1D onset.
@en
P2093
Henry A Erlich
Janelle A Noble
P2860
P304
P356
10.1016/J.HUMIMM.2004.12.001
P577
2005-03-01T00:00:00Z