Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research.
about
A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisCripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cellsActivation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferationReciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancerEpidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptorsProlonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neuHER2 expression in cervical cancer as a potential therapeutic targetTyrosine kinase signalling in breast cancer. Epidermal growth factor receptor: convergence point for signal integration and diversificationAt the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of boneThe Under-Appreciated Promiscuity of the Epidermal Growth Factor Receptor FamilyThe HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitorComparative methodological analysis of erbB-2/HER-2 gene dosage, chromosomal copy number and protein overexpression in breast carcinoma tissues for diagnostic useExpression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour typesChanges in ErbB2 (her-2/neu), ErbB3, and ErbB4 during growth, differentiation, and apoptosis of normal rat mammary epithelial cellsEmbryo-uterine interactions via the neuregulin family of growth factors during implantation in the mouseLeptin/HER2 crosstalk in breast cancer: in vitro study and preliminary in vivo analysisEmerging therapies in gastrointestinal cancers.Role of receptor tyrosine kinases and their ligands in glioblastoma.Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway.A strain-independent postnatal neurodegeneration in mice lacking the EGF receptorSTAT signaling in head and neck cancer.Specific antibody-receptor interactions trigger InlAB-independent uptake of Listeria monocytogenes into tumor cell lines.Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells.Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormonesHER2-mediated effects on EGFR endosomal sorting: analysis of biophysical mechanismsThe relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells.EGFR signaling in breast cancer: bad to the bone.Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus.Profiling epidermal growth factor receptor and heregulin receptor 3 heteromerization using receptor tyrosine kinase heteromer investigation technology.Small sized EGFR1 and HER2 specific bifunctional antibody for targeted cancer therapyThe EGF receptor family--multiple roles in proliferation, differentiation, and neoplasia with an emphasis on HER4A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumorsSignalling mechanisms regulating phenotypic changes in breast cancer cells.Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR-NF-κB signalling pathway in human epidermoid carcinoma A431 cells.The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro.Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinomaErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit.Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization.
P2860
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P2860
Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Heterodimerization and functio ...... ns for breast cancer research.
@en
type
label
Heterodimerization and functio ...... ns for breast cancer research.
@en
prefLabel
Heterodimerization and functio ...... ns for breast cancer research.
@en
P2093
P356
P1476
Heterodimerization and functio ...... ns for breast cancer research.
@en
P2093
P2888
P304
P356
10.1007/BF00694752
P407
P577
1995-07-01T00:00:00Z
P6179
1037118979