In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit.
about
Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cellsEmerging therapeutic options for Philadelphia-positive acute lymphocytic leukemia.Advances and controversies in the diagnosis, pathogenesis, and treatment of systemic mastocytosis.Proteasome inhibition upregulates Bim and induces caspase-3-dependent apoptosis in human mast cells expressing the Kit D816V mutation.Juxtamembrane-type c-kit gene mutation found in aggressive systemic mastocytosis induces imatinib-resistant constitutive KIT activation.Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases.Structure-based de novo design and identification of D816V mutant-selective c-KIT inhibitors.
P2860
Q26740953-05612055-1EF2-4DE1-ACC0-5969E37F37C3Q36758604-8BECE946-D683-4690-9F37-01CBB9BB44B9Q37892475-C716F79F-25B3-4976-8CBA-E0107C3E232DQ39244862-2AF897B3-AEE9-4774-996C-2ADDCB708FFAQ40177813-4CBB0116-026D-414A-8834-9F0A365648CDQ40281928-DADAF4CA-BE4E-42D5-9B12-04C17B201004Q53279724-874069EF-AC41-4B83-ADA7-73E9D5144DB4
P2860
In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
In vitro and in vivo activity ...... ctivation-loop mutants of Kit.
@en
type
label
In vitro and in vivo activity ...... ctivation-loop mutants of Kit.
@en
prefLabel
In vitro and in vivo activity ...... ctivation-loop mutants of Kit.
@en
P2093
P1433
P1476
In vitro and in vivo activity ...... ctivation-loop mutants of Kit.
@en
P2093
Amie S Corbin
Chester A Metcalf
David Dalgarno
Ian J Griswold
John Iuliucci
Joseph Snodgrass
Michael W N Deininger
Raji Sundaramoorthi
Scott Wardwell
Shadmehr Demehri
P304
P356
10.1182/BLOOD-2004-12-4771
P407
P577
2005-03-03T00:00:00Z