Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).
about
Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domainABL tyrosine kinases: evolution of function, regulation, and specificityGene expression profiling identifies a subset of adult T-cell acute lymphoblastic leukemia with myeloid-like gene features and over-expression of miR-223Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domainLoss of dystrophin and the microtubule-binding protein ELP-1 causes progressive paralysis and death of adult C. elegans.The C. elegans EMAP-like protein, ELP-1 is required for touch sensation and associates with microtubules and adhesion complexes.Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults.Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell contextComprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemiaQuantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling.RCSD1-ABL1 Translocation Associated with IKZF1 Gene Deletion in B-Cell Acute Lymphoblastic Leukemia.Chronic myeloproliferative disorders: a tyrosine kinase tale.Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disordersNotch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia.TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage.The NOTCH signaling pathway: role in the pathogenesis of T-cell acute lymphoblastic leukemia and implication for therapy.Aberrant cytokine signaling in leukemia.Aberrant signaling in T-cell acute lymphoblastic leukemia: biological and therapeutic implications.Abl tyrosine kinases in T-cell signalingMolecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia.ABL1 fusion genes in hematological malignancies: a review.Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies.T-cell acute lymphoblastic leukaemia: recent molecular biology findings.The molecular basis of T cell acute lymphoblastic leukemiaGenomic characterization of acute leukemias.Transcription factor mutations in myelodysplastic/myeloproliferative neoplasmsPediatric T-cell acute lymphoblastic leukemia.Development of a siRNA and shRNA screening system based on a kinase fusion protein.Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia.Identification of interconnected markers for T-cell acute lymphoblastic leukemiaA novel dasatinib-sensitive RCSD1-ABL1 fusion transcript in chemotherapy-refractory adult pre-B lymphoblastic leukemia with t(1;9)(q24;q34).Poor responses to tyrosine kinase inhibitors in a child with precursor B-cell acute lymphoblastic leukemia with SNX2-ABL1 chimeric transcript.Identification and characterization of activating ABL1 1b kinase mutations: impact on sensitivity to ATP-competitive and allosteric ABL1 inhibitors.Newly diagnosed acute lymphoblastic leukemia in China (I): abnormal genetic patterns in 1346 childhood and adult cases and their comparison with the reports from Western countries.RCSD1-ABL1-positive B lymphoblastic leukemia is sensitive to dexamethasone and tyrosine kinase inhibitors and rapidly evolves clonally by chromosomal translocations.A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia.Acute lymphoblastic leukemiaAcute Lymphoblastic Leukemia
P2860
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P2860
Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Fusion of EML1 to ABL1 in T-ce ...... with cryptic t(9;14)(q34;q32).
@en
type
label
Fusion of EML1 to ABL1 in T-ce ...... with cryptic t(9;14)(q34;q32).
@en
prefLabel
Fusion of EML1 to ABL1 in T-ce ...... with cryptic t(9;14)(q34;q32).
@en
P2093
P50
P1433
P1476
Fusion of EML1 to ABL1 in T-ce ...... with cryptic t(9;14)(q34;q32)
@en
P2093
Anne Hagemeijer
Carlos Graux
Iwona Wlodarska
Johan Maertens
Maria D Odero
Nicole Mentens
Peter Marynen
Riet Somers
P304
P356
10.1182/BLOOD-2004-12-4897
P407
P577
2005-02-15T00:00:00Z