Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.

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Understanding specific functions of PARP-2: new lessons for cancer therapy Optimized AAV rh.10 Vectors That Partially Evade Neutralizing Antibodies during Hepatic Gene Transfer.

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Q28067486-6CD69B99-81AC-48E7-8E9C-3E8B60F9393F Q40097321-40D71CB9-CB16-4336-9C43-63ED8ED277D6

P2860

Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.

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http://www.wikidata.org/entity/Q40458807

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

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2015年论文

@zh-cn

name

Synergistic inhibition of PARP ...... s during hepatic gene therapy.

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type

Item

label

Synergistic inhibition of PARP ...... s during hepatic gene therapy.

@en

prefLabel

Synergistic inhibition of PARP ...... s during hepatic gene therapy.

@en

P1476

Synergistic inhibition of PARP ...... rs during hepatic gene therapy

@en

P2093

Giridhara R Jayandharan

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P2860

Vision 1 year after gene therapy for Leber's congenital amaurosis

Self-complementary AAVs induce more potent transgene product-specific immune responses compared to a single-stranded genome

The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1

Safety and efficacy of gene transfer for Leber's congenital amaurosis

The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

Proteasome inhibition is partially effective in attenuating pre-existing immunity against recombinant adeno-associated viral vectors

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

The immunopathogenesis of sepsis

A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes.

P304

154-166

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P31

scholarly article

P356

10.1002/EJI.201545867

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English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Balakrishnan S Ramakrishna

Sangeetha Hareendran

P577

2015-11-05T00:00:00Z

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P698

26443873

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P921

gene therapy

NF-κB

Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.

about

P2860

P2860

Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.

description

name

type

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prefLabel

P1433

P1476

P2093

P2860

P304

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P356

P407

P433

P478

P50

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921