Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor.
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Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesPACAP inhibits tumor growth and interferes with clusterin in cervical carcinomasInterleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progressionFuchs endothelial corneal dystrophy: current perspectivesDAB2IP in cancerATM regulates insulin-like growth factor 1-secretory clusterin (IGF-1-sCLU) expression that protects cells against senescenceClusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathwayClusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survivalClusterin expression in normal mucosa and colorectal cancer.TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer.Lineage-specific restraint of pituitary gonadotroph cell adenoma growth.Longevity is impacted by growth hormone action during early postnatal periodZinc sensing receptor signaling, mediated by GPR39, reduces butyrate-induced cell death in HT29 colonocytes via upregulation of clusterin.Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer.Fuchs endothelial corneal dystrophyDoes pre-existing diabetes affect prostate cancer prognosis? A systematic review.Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complexAntiangiogenic antitumor activities of IGFBP-3 are mediated by IGF-independent suppression of Erk1/2 activation and Egr-1-mediated transcriptional eventsThe tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60.CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factorGrowth regulation via insulin-like growth factor binding protein-4 and -2 in association with mutant K-ras in lung epithelia.Molecular bases of corneal endothelial dystrophies.Clusterin is a potential molecular predictor for ovarian cancer patient's survival: targeting clusterin improves response to paclitaxel.Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations.Egr-1 binds the GnRH promoter to mediate the increase in gene expression by insulin.Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling.Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect.Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis.Clusterin and FOXL2 act concordantly to regulate pituitary gonadotroph adenoma growthCandidate protein biodosimeters of human exposure to ionizing radiation.Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases.Efficient suppression of secretory clusterin levels by polymer-siRNA nanocomplexes enhances ionizing radiation lethality in human MCF-7 breast cancer cells in vitro.The mechanism of DAB2IP in chemoresistance of prostate cancer cells.eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells.Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase.IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells.Increased clusterin expression in Fuchs' endothelial dystrophy.Clusterin and chemoresistance.Emerging anticancer therapeutic targets and the cardiovascular system: is there cause for concern?Transcriptional mechanisms regulating Ca(2+) homeostasis.
P2860
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P2860
Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Delayed activation of insulin- ...... ession, a pro-survival factor.
@en
type
label
Delayed activation of insulin- ...... ession, a pro-survival factor.
@en
prefLabel
Delayed activation of insulin- ...... ession, a pro-survival factor.
@en
P2093
P2860
P356
P1476
Delayed activation of insulin- ...... ession, a pro-survival factor.
@en
P2093
David A Boothman
Eva Cataldo
Konstantin Leskov
Lindsey D Mayo
Meghan Beman
Shinako Araki
Tracy Criswell
P2860
P304
14212-14221
P356
10.1074/JBC.M412569200
P407
P577
2005-02-02T00:00:00Z