Inhibition of tumor growth, angiogenesis, and tumor cell proliferation by a small molecule inhibitor of c-Jun N-terminal kinase.
about
Targeting c-Jun and JunB proteins as potential anticancer cell therapyCXCL13 mediates prostate cancer cell proliferation through JNK signalling and invasion through ERK activationSelective inhibition of JNK with a peptide inhibitor attenuates pain hypersensitivity and tumor growth in a mouse skin cancer pain modelc-Jun-NH2-kinase-1 inhibition leads to antitumor activity in ovarian cancer.Perturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation.HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.Oral administration of blueberry inhibits angiogenic tumor growth and enhances survival of mice with endothelial cell neoplasmCalcium-activated K+ channels increase cell proliferation independent of K+ conductance.Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2Kc-Jun N-terminal kinase inhibitor II (SP600125) activates Mullerian inhibiting substance type II receptor-mediated signal transduction.Src promotes cutaneous wound healing by regulating MMP-2 through the ERK pathway.LY2228820 dimesylate, a selective inhibitor of p38 mitogen-activated protein kinase, reduces angiogenic endothelial cord formation in vitro and in vivo.MKK signaling and vascularization.Emerging role of MAP kinase pathways as therapeutic targets in COPD.Matrix metalloproteinase-activated anthrax lethal toxin inhibits endothelial invasion and neovasculature formation during in vitro morphogenesis.Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development.JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.c-Jun N-terminal kinase in pancreatic tumor stroma augments tumor development in mice.Dual specificity phosphatase 1 expression inversely correlates with NF-κB activity and expression in prostate cancer and promotes apoptosis through a p38 MAPK dependent mechanism.Molecular angiogenic events of a two-herb wound healing formula involving MAPK and Akt signaling pathways in human vascular endothelial cells.Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.Integrative Analysis of mRNA, microRNA, and Protein Correlates of Relative Cerebral Blood Volume Values in GBM Reveals the Role for Modulators of Angiogenesis and Tumor Proliferation.c-Jun NH2 terminal kinase activation and decreased expression of mitogen-activated protein kinase phosphatase-1 play important roles in invasion and angiogenesis of urothelial carcinomas.Neuroprotection by NMDA preconditioning against glutamate cytotoxicity is mediated through activation of ERK 1/2, inactivation of JNK, and by prevention of glutamate-induced CREB inactivation.
P2860
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P2860
Inhibition of tumor growth, angiogenesis, and tumor cell proliferation by a small molecule inhibitor of c-Jun N-terminal kinase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Inhibition of tumor growth, an ...... or of c-Jun N-terminal kinase.
@en
type
label
Inhibition of tumor growth, an ...... or of c-Jun N-terminal kinase.
@en
prefLabel
Inhibition of tumor growth, an ...... or of c-Jun N-terminal kinase.
@en
P2093
P356
P1476
Inhibition of tumor growth, an ...... or of c-Jun N-terminal kinase.
@en
P2093
Bernd Stein
Bruce W Ennis
Graham K Bilter
John K Westwick
Kent A Smith
Kimberly E Fultz
Michael Boluro-Ajayi
P304
P356
10.1124/JPET.104.078873
P407
P577
2004-12-30T00:00:00Z