Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters.
about
Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cellsThe mitochondrial heme exporter FLVCR1b mediates erythroid differentiationOptimization of feline immunodeficiency virus vectors for RNA interferenceSUMF1 enhances sulfatase activities in vivo in five sulfatase deficienciesLong-term survival of human neural stem cells in the ischemic rat brain upon transient immunosuppressionPSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical modelsRbfox1 downregulation and altered calpain 3 splicing by FRG1 in a mouse model of Facioscapulohumeral muscular dystrophy (FSHD)Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy.Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.The ets-related transcription factor GABP directs bidirectional transcription.A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging.Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in Jurkat T-cellsLive cell monitoring of hiPSC generation and differentiation using differential expression of endogenous microRNAs.Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophyMicroRNAs shape circadian hepatic gene expression on a transcriptome-wide scale.Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.Immunobiological characterization of cancer stem cells isolated from glioblastoma patients.Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia.Dose-dependent neuroprotection of VEGF₁₆₅ in Huntington's disease striatumHuman fetal liver stromal cells that overexpress bFGF support growth and maintenance of human embryonic stem cellsAnti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia model4-1BB and CD28 signaling plays a synergistic role in redirecting umbilical cord blood T cells against B-cell malignanciesFamilial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidaseMolecular imaging of transcriptional regulation during inflammationTransfer, analysis, and reversion of the fibrous dysplasia cellular phenotype in human skeletal progenitors.Angiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cellsOncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.Exploiting microRNA regulation for genetic engineering.High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries.Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history.Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer.Specific micro RNA-regulated TetR-KRAB transcriptional control of transgene expression in viral vector-transduced cells.SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactionsHepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors.Easy quantitative assessment of genome editing by sequence trace decomposition.Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche.Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter.The 9L(LUC)/Wistar rat glioma model is not suitable for immunotherapy.
P2860
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P2860
Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Coordinate dual-gene transgene ...... hetic bidirectional promoters.
@en
type
label
Coordinate dual-gene transgene ...... hetic bidirectional promoters.
@en
prefLabel
Coordinate dual-gene transgene ...... hetic bidirectional promoters.
@en
P2860
P50
P356
P1433
P1476
Coordinate dual-gene transgene ...... hetic bidirectional promoters.
@en
P2093
Alessandra Biffi
Elisa Vigna
P2860
P2888
P304
P356
10.1038/NBT1049
P577
2004-12-26T00:00:00Z
P5875
P6179
1003260082