MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling.
about
Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiationIdentification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1Multiple roles for emerin: implications for Emery-Dreifuss muscular dystrophyRegulation of postnatal bone homeostasis by TGFβLamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biologyAsi1 is an inner nuclear membrane protein that restricts promoter access of two latent transcription factors.Inner nuclear membrane proteins Asi1, Asi2, and Asi3 function in concert to maintain the latent properties of transcription factors Stp1 and Stp2.The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivoNuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinasesNuclear envelope transmembrane proteins (NETs) that are up-regulated during myogenesis.Lamin A/C is a risk biomarker in colorectal cancer.Diseases of the nuclear envelope.Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans.Lamin-binding ProteinsThe self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation.Nuclear envelope protein MAN1 regulates clock through BMAL1The lamin protein family."Laminopathies": a wide spectrum of human diseases.Inner nuclear membrane proteins: impact on human disease.Direct binding of nuclear membrane protein MAN1 to emerin in vitro and two modes of binding to barrier-to-autointegration factor.Mapping of protein- and chromatin-interactions at the nuclear laminaIdentification of differential protein interactors of lamin A and progerinWnt signaling pathway pharmacogenetics in non-small cell lung cancerLmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes.Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling.Nuclear membrane diversity: underlying tissue-specific pathologies in disease?The Buschke-Ollendorff syndrome: a case report of simultaneous osteo-cutaneous malformations in the hand.Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins.The cellular mastermind(?)-mechanotransduction and the nucleus.The nuclear envelope proteome differs notably between tissues.What MAN1 does to the Smads. TGFbeta/BMP signaling and the nuclear envelope.Gene silencing at the nuclear periphery.Dependence of diffusional mobility of integral inner nuclear membrane proteins on A-type lamins.Tissue-specific defects are caused by loss of the Drosophila MAN1 LEM domain protein.The inner nuclear envelope as a transcription factor resting place.The Drosophila nuclear lamina protein otefin is required for germline stem cell survival.Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokersGenome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional programAdult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches.Antitransforming growth factor-beta therapy in fibrosis: recent progress and implications for systemic sclerosis.
P2860
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P2860
MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
MAN1, an integral protein of t ...... growth factor-beta signaling.
@en
type
label
MAN1, an integral protein of t ...... growth factor-beta signaling.
@en
prefLabel
MAN1, an integral protein of t ...... growth factor-beta signaling.
@en
P2093
P2860
P356
P1476
MAN1, an integral protein of t ...... growth factor-beta signaling.
@en
P2093
P2860
P304
P356
10.1093/HMG/DDI040
P577
2004-12-15T00:00:00Z