Alternative phospholipase D/mTOR survival signal in human breast cancer cells. - Wikidata - wikimedia - TriplyDB

Alternative phospholipase D/mTOR survival signal in human breast cancer cells.

Alternative phospholipase D/mTOR survival signal in human breast cancer cells.

http://www.wikidata.org/entity/Q40484574

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Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor Functional regulation of phospholipase D expression in cancer and inflammation Structural and functional analysis of novel human cytochrome C targets in apoptosis The signaling petri net-based simulator: a non-parametric strategy for characterizing the dynamics of cell-specific signaling networks Halofuginone Synergistically Enhances Anti-Proliferation of Rapamycin in T Cells and Reduces Cytotoxicity of Cyclosporine in Cultured Renal Tubular Epithelial Cells Phospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells.A comprehensive model that explains the regulation of phospholipase D2 activity by phosphorylation-dephosphorylation.Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc.Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells.Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation.Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway.Blocking anaplerotic entry of glutamine into the TCA cycle sensitizes K-Ras mutant cancer cells to cytotoxic drugs.Phospholipase D: enzymology, functionality, and chemical modulation High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.Novel Bioluminescent Activatable Reporter for Src Tyrosine Kinase Activity in Living Mice.Paxillin phosphorylation and complexing with Erk and FAK are regulated by PLD activity in MDA-MB-231 cells Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle.PLD1 is overexpressed in an ER-negative MCF-7 cell line variant and a subset of phospho-Akt-negative breast carcinomas A Repertoire of MicroRNAs Regulates Cancer Cell Starvation by Targeting Phospholipase D in a Feedback Loop That Operates Maximally in Cancer Cells A Single Nucleotide Polymorphism in the Phospholipase D1 Gene is Associated with Risk of Non-Small Cell Lung Cancer.Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras.The potential for phospholipase D as a new therapeutic target.Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest.Phosphatidic acid and lipid-sensing by mTOR Mechanisms of mammalian target of rapamycin inhibition in sarcoma: present and future.Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells.Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells.Targeting mTOR with rapamycin: one dose does not fit all A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis.Phosphatidic acid, phospholipase D and tumorigenesis.Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis.Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy.Metabolic control of signalling pathways and metabolic auto-regulation.

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Alternative phospholipase D/mTOR survival signal in human breast cancer cells.

http://www.wikidata.org/entity/Q40484574

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年學術文章

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2005年學術文章

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name

Alternative phospholipase D/mTOR survival signal in human breast cancer cells.

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type

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Alternative phospholipase D/mTOR survival signal in human breast cancer cells.

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Alternative phospholipase D/mTOR survival signal in human breast cancer cells.

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Alternative phospholipase D/mTOR survival signal in human breast cancer cells.

@en

P2093

David A Foster

http://www.w3.org/2001/XMLSchema#string

Vanessa Rodrik

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Yuhong Chen

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The Hallmarks of Cancer

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

Transmodulation between phospholipase D and c-Src enhances cell proliferation

Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

TOR, a central controller of cell growth.

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

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672-679

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10.1038/SJ.ONC.1208099

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4

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24

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1001126097

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15580312

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