Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C).
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Association between SLCO1B1 -521T>C and -388A>G polymorphisms and risk of statin-induced adverse drug reactions: A meta-analysisRapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Cyanobacterial Toxins of the Laurentian Great Lakes, Their Toxicological Effects, and Numerical Limits in Drinking WaterSeveral conserved positively charged amino acids in OATP1B1 are involved in binding or translocation of different substratesThe influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.Pharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin responseRare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate dispositionCommon nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS studyStatin response and pharmacokinetics variants.Association Between SLCO1B1 Gene T521C Polymorphism and Statin-Related Myopathy Risk: A Meta-Analysis of Case-Control StudiesRole of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination.Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans.Inherited variation in OATP1B1 is associated with treatment outcome in acute myeloid leukemia.Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1Role of OATP transporters in the disposition of drugs.Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis.Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability - considerations for drug development.Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption.Transporter assays as useful in vitro tools in drug discovery and development.Global analysis of genetic variation in SLCO1B1.Intracellular accumulation of atazanavir/ritonavir according to plasma concentrations and OATP1B1, ABCB1 and PXR genetic polymorphisms.PharmGKB very important pharmacogene: SLCO1B1.Effects of natural products on the function of human organic anion transporting polypeptide 1B1.Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase.Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population.Pharmacokinetic Changes during Pregnancy According to Genetic Variants: A Prospective Study in HIV-infected Patients Receiving Atazanavir/Ritonavir.Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers.SLCO1B1 haplotypes are not associated with atorvastatin-induced myalgia in Brazilian patients with familial hypercholesterolemia.Rapid genotyping of the OATP1B1 polymorphisms A388G and T521C with real-time PCR FRET assays.Identification of Genetic Risk Factors for Neonatal Hyperbilirubinemia in Fujian Province, Southeastern China: A Case-Control Study
P2860
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P2860
Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C).
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Functional analysis of single ...... transporter OATP1B1 (OATP-C).
@en
type
label
Functional analysis of single ...... transporter OATP1B1 (OATP-C).
@en
prefLabel
Functional analysis of single ...... transporter OATP1B1 (OATP-C).
@en
P2093
P1476
Functional analysis of single ...... transporter OATP1B1 (OATP-C).
@en
P2093
Hiroshi Suzuki
Ichiro Ieiri
Kenji Otsubo
Megumi Iwai
Yuichi Sugiyama
P304
P356
10.1097/00008571-200411000-00006
P577
2004-11-01T00:00:00Z