Shedding and gamma-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43. - Wikidata - wikimedia - TriplyDB

Shedding and gamma-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43.

Shedding and gamma-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43.

http://www.wikidata.org/entity/Q40492938

about

Presenilin/gamma-secretase and alpha-secretase-like peptidases cleave human MHC Class I proteins Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria Pathological and physiological functions of presenilins.CD43 promotes cells transformation by preventing merlin-mediated contact inhibition of growth Post-translational regulation of signaling mucins.Substrate specificity of gamma-secretase and other intramembrane proteases.Trafficking of receptor tyrosine kinases to the nucleus Intracellular patterns of sialophorin expression define a new molecular classification of breast cancer and represent new targets for therapy.Aberrant glycosylation as biomarker for cancer: focus on CD43.The structure and function of Alzheimer's gamma secretase enzyme complex.The many substrates of presenilin/γ-secretase.The physiology of the β-amyloid precursor protein intracellular domain AICD.Transmembrane Mucins: Signaling Receptors at the Intersection of Inflammation and Cancer.CD43 in the nucleus and cytoplasm of lung cancer is a potential therapeutic target.The cleavage of neutrophil leukosialin (CD43) by cathepsin G releases its extracellular domain and triggers its intramembrane proteolysis by presenilin/gamma-secretase.Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates.

P2860

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P2860

Shedding and gamma-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43.

http://www.wikidata.org/entity/Q40492938

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh

2005年學術文章

@zh-hant

name

Shedding and gamma-secretase-m ...... the mucin-type molecule CD43.

@en

type

label

Shedding and gamma-secretase-m ...... the mucin-type molecule CD43.

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prefLabel

Shedding and gamma-secretase-m ...... the mucin-type molecule CD43.

@en

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P1433

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P1476

Shedding and gamma-secretase-m ...... the mucin-type molecule CD43.

@en

P2093

Christian X Andersson

http://www.w3.org/2001/XMLSchema#string

Dan Baeckström

http://www.w3.org/2001/XMLSchema#string

Gunnar C Hansson

http://www.w3.org/2001/XMLSchema#string

Julia Fernandez-Rodriguez

http://www.w3.org/2001/XMLSchema#string

Sirle Laos

http://www.w3.org/2001/XMLSchema#string

P2860

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.

Amino acid sequence of human plasma galactoglycoprotein: identity with the extracellular region of CD43 (sialophorin)

CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes

Proteolytic processing and cell biological functions of the amyloid precursor protein

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide

Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland

MUC1, the renaissance molecule

P304

377-384

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10.1042/BJ20041387

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P433

Pt 2

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P478

387

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Christian Haass

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2005-04-01T00:00:00Z

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51371773

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15540986

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1134965

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