Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism.
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Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblastsInduction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells: biological correlates and molecular targets.Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1.Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs).Depletion of insulin receptor substrate 2 reverses oncogenic transformation induced by v-src.Targeting PKC delta-mediated topoisomerase II beta overexpression subverts the differentiation block in a retinoic acid-resistant APL cell line.Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors.Nuclear insulin receptor substrate-1 activates promoters of cell cycle progression genes.A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration.Upregulation of the insulin receptor and type I insulin-like growth factor receptor are early events in hepatocarcinogenesis.Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL)
P2860
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P2860
Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
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name
Retinoic acid mediates degrada ...... via a PKC-dependant mechanism.
@en
type
label
Retinoic acid mediates degrada ...... via a PKC-dependant mechanism.
@en
prefLabel
Retinoic acid mediates degrada ...... via a PKC-dependant mechanism.
@en
P2093
P2860
P356
P1433
P1476
Retinoic acid mediates degrada ...... via a PKC-dependant mechanism.
@en
P2093
Eva Surmacz
Hoi-Ying Shiu
Sonia V del Rincón
Wilson H Miller
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208104
P407
P577
2004-12-01T00:00:00Z
P5875
P6179
1008545480