Cyclin D1 proteolysis: a retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells
about
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionPhosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation.UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemiaThe natural tumor suppressor protein maspin and potential application in non small cell lung cancerExpression of cyclin D1/2 in the lungs of strain A/J mice fed chemopreventive agentsCyclin proteolysis as a retinoid cancer prevention mechanism.Bexarotene plus erlotinib suppress lung carcinogenesis independent of KRAS mutations in two clinical trials and transgenic models.Prevention of bronchial hyperplasia by EGFR pathway inhibitors in an organotypic culture modelRARβ2 hypermethylation is associated with poor recurrence-free survival in never-smokers with adenocarcinoma of the lungViral defense, carcinogenesis and ISG15: novel roles for an old ISGChemoprevention of lung cancer: concepts and strategies.Evidence for the ubiquitin protease UBP43 as an antineoplastic target.Pulmonary availability of isotretinoin in rats after inhalation of a powder aerosolRepression of exogenous gene expression by the retinoic acid target gene G0S2.UBE1L causes lung cancer growth suppression by targeting cyclin D1.Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancerGlobal assessment of genetic variation influencing response to retinoid chemoprevention in head and neck cancer patients.Microarray analysis uncovers retinoid targets in human bronchial epithelial cells.All-Trans-Retinoic Acid Stimulates Overexpression of Tumor Protein D52 (TPD52, Isoform 3) and Neuronal Differentiation of IMR-32 Cells.Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism.RARgamma acts as a tumor suppressor in mouse keratinocytes.Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation.The roles of JNK1 and Stat3 in the response of head and neck cancer cell lines to combined treatment with all-trans-retinoic acid and 5-fluorouracil.Retinoic acid-mediated growth arrest requires ubiquitylation and degradation of the F-box protein Skp2.Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation.Retinoic acid stabilizes p27Kip1 in EBV-immortalized lymphoblastoid B cell lines through enhanced proteasome-dependent degradation of the p45Skp2 and Cks1 proteins.Isotretinoin therapy induces DNA oxidative damage.Biomolecular markers as intermediate end points in chemoprevention trials of upper aerodigestive tract cancer.
P2860
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P2860
Cyclin D1 proteolysis: a retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
@ast
Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
@en
Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
@nl
type
label
Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
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Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
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Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
@nl
prefLabel
Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
@ast
Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
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Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
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P2093
P2860
P356
P1476
Cyclin D1 proteolysis: a retin ...... man bronchial epithelial cells
@en
P2093
E Dmitrovsky
J Langenfeld
M I Dawson
P2860
P304
P356
10.1093/JNCI/91.4.373
P407
P577
1999-02-01T00:00:00Z