FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation.
about
The emerging role of FTY720 (Fingolimod) in cancer treatmentSphingolipids in spinal cord injuryTherapeutic effects of novel sphingosine-1-phosphate receptor agonist W-061 in murine DSS colitisFTY720 Induces Autophagy-Associated Apoptosis in Human Oral Squamous Carcinoma Cells, in Part, through a Reactive Oxygen Species/Mcl-1-Dependent Mechanism.FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.Differential regulation of autophagy and cell viability by ceramide species.Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.Targeted therapy of hepatocellular cancer.Tyrosine kinase inhibitors to treat liver cancer.Protein phosphatase 2A: a target for anticancer therapy.The antineoplastic properties of FTY720: evidence for the repurposing of fingolimod.Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod).FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system.Melatonin prevents deregulation of the sphingosine kinase/sphingosine 1-phosphate signaling pathway in a mouse model of diethylnitrosamine-induced hepatocellular carcinoma.FTY720 induces cell cycle arrest and apoptosis of rat glomerular mesangial cells.Inhibition of hydrogen peroxide signaling by 4-hydroxynonenal due to differential regulation of Akt1 and Akt2 contributes to decreases in cell survival and proliferation in hepatocellular carcinoma cells.Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis.Non-phosphorylated FTY720 induces apoptosis of human microglia by activating SREBP2.Pharmacological manipulation of the akt signaling pathway regulates myxoma virus replication and tropism in human cancer cells.Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B."Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer.Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitroFTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity.Roles of PI3-K/Akt pathways in nanoparticle realgar powders-induced apoptosis in U937 cells.FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts.More than Just an Immunosuppressant: The Emerging Role of FTY720 as a Novel Inducer of ROS and Apoptosis.Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro
P2860
Q26748927-DAE8891E-95ED-4249-A62B-2370F84B2D24Q27026103-646735B1-08CE-47CC-B1FD-76B9BB7A2597Q28740568-7150C44F-FED7-4B49-8E48-38751F504958Q33912023-C65B5EB8-FB85-4546-BC37-1480E67D7E44Q35945171-A0E3242E-1C03-4888-BA79-8B42BDF1ECBFQ36214943-D9C6D0BF-192F-49A2-8AA4-0000C5F6ABFFQ36886386-482A8B73-3D0E-4CC3-88F5-DB7557DCF1A2Q37298313-01E87DEE-9D6C-4DF2-954C-12AE9EBBB5C5Q37674624-E179477D-4313-4C9C-A596-5F69B57297DBQ37686529-23779F5E-6484-46C9-B460-4785683D666AQ38103646-285947FA-E8F5-40DA-950C-8318197D2136Q38546700-B047BA92-4A75-4B88-8671-B8760E590124Q38607090-D3D3A409-E34F-46E5-BAD0-06640852BC3EQ39114974-D7868134-CBD8-464E-8D87-7B1BC53B0858Q39328422-C946C182-A790-4080-8ED5-E98D831B0305Q39349191-1FD98DBB-1E42-4926-B708-3F2CC94B38A0Q39349474-4B24B757-9C2D-4943-8F52-135EAACA6E9AQ39445561-F4E0DF3E-9274-441F-B29D-6C3B7FB3BA8AQ39553011-1B25337B-A0C1-4499-A9FB-FE4207C5DBF2Q39610261-AD678B76-0C31-4892-8F79-998CD6621B7CQ40329956-DADB10AA-E276-4D7E-B427-8116BFDDCD75Q40354649-AE5CD476-C445-44ED-A089-07FFED7B3219Q41661043-265A715E-1D49-4B3F-B6D0-E72983FED7A0Q41669466-A3E37B85-49C2-4561-AB49-64804EB2CDD1Q43203316-4877155D-074F-4FF9-82EB-F415A97D7CF8Q46734565-9709CCBF-6001-48D1-B25C-0E10221A6626Q52714457-5412C505-1F05-4D9C-B59E-D836AF21EBCEQ55281738-C7B39D27-44EE-432D-9015-D81B1D44AAD3Q59324551-DA12C77D-2CFD-4C5C-B8FC-24EDFF3FE173
P2860
FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
FTY720 induces apoptosis of hu ...... ediated Akt dephosphorylation.
@en
type
label
FTY720 induces apoptosis of hu ...... ediated Akt dephosphorylation.
@en
prefLabel
FTY720 induces apoptosis of hu ...... ediated Akt dephosphorylation.
@en
P2093
P356
P1433
P1476
FTY720 induces apoptosis of hu ...... ediated Akt dephosphorylation.
@en
P2093
Chris K Sun
Irene O Ng
Joanna W Ho
Kevin T Ng
Sheung Tat Fan
Terence K Lee
Xiang Hong Wang
Yong Chuan Wong
P304
P356
10.1093/CARCIN/BGH250
P407
P577
2004-08-05T00:00:00Z