Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites.
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P1343
Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analogTopotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase IThe indenoisoquinoline noncamptothecin topoisomerase I inhibitors: update and perspectives.Free energy calculations reveal rotating-ratchet mechanism for DNA supercoil relaxation by topoisomerase IB and its inhibition.SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I.Structure and hydration of the DNA-human topoisomerase I covalent complex.Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin.Human topoisomerase I promotes HIV-1 proviral DNA synthesis: implications for the species specificity and cellular tropism of HIV-1 infection.Topotecan in the management of cervical cancer.Cloning and characterization of the gene for the somatic form of DNA topoisomerase I from Xenopus laevisImmunohistochemical detection of DNA topoisomerase I in formalin fixed, paraffin wax embedded normal tissues and in ovarian carcinomas.Protein concerted motions in the DNA-human topoisomerase I complex.Role of the linker domain and the 203-214 N-terminal residues in the human topoisomerase I DNA complex dynamics.Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors.Identification and characterization of a deletion mutant of DNA topoisomerase I mRNA in a camptothecin-resistant subline of human colon carcinoma.Establishment and characterization of 6-[[2-(Dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride (TAS-103)-resistant cell lines.Retroviral expression of a mutant (Gly-533) human DNA topoisomerase I cDNA confers a dominant form of camptothecin resistance.Action models for the antitumor drug camptothecin: formation of alkali-labile complex with DNA and inhibition of human DNA topoisomerase I.Gene mutation analysis and quantitation of DNA topoisomerase I in previously untreated non-small cell lung carcinomas.Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5.Substitutions in Spodoptera exigua topoisomerase I modulate its relaxation activity and camptothecin sensitivity.In vitro antitumor activity of TAS-103, a novel quinoline derivative that targets topoisomerases I and II.No alteration in DNA topoisomerase I gene related to CPT-11 resistance in human lung cancer.
P2860
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P2860
Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Molecular cloning of a cDNA of ...... ntification of mutation sites.
@en
type
label
Molecular cloning of a cDNA of ...... ntification of mutation sites.
@en
prefLabel
Molecular cloning of a cDNA of ...... ntification of mutation sites.
@en
P2093
P2860
P356
P1476
Molecular cloning of a cDNA of ...... ntification of mutation sites.
@en
P2093
Kjeldsen E
Nishikawa K
Patterson E
P2860
P356
10.1093/NAR/19.1.69
P577
1991-01-01T00:00:00Z