Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin.
about
The domain organization of human topoisomerase IBiochemical and biophysical analyses of recombinant forms of human topoisomerase IA mutation in Escherichia coli DNA gyrase conferring quinolone resistance results in sensitivity to drugs targeting eukaryotic topoisomerase IIImportance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action.Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolationThe role of histidine 632 in catalysis by human topoisomerase I.Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sitesTopoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae.Role for topoisomerase 1 in transcription-associated mutagenesis in yeastIn vivo sequencing of camptothecin-induced topoisomerase I cleavage sites in human colon carcinoma cells.Use of double-stranded DNA mini-circles to characterize the covalent topoisomerase-DNA complex.Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae.Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenineMolecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions.Mutation of a conserved serine residue in a quinolone-resistant type II topoisomerase alters the enzyme-DNA and drug interactions.Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.Preferential binding of human topoisomerase I to superhelical DNA.Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes.DNA sequence selectivity of human topoisomerase I-mediated DNA cleavage induced by camptothecin.Sequence-selective DNA cleavage by a topoisomerase I poison, NB-506.Topoisomerase I and Genome Stability: The Good and the Bad.
P2860
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P2860
Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin.
description
1993 nî lūn-bûn
@nan
1993 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Induction of cleavage in topoi ...... e and absence of camptothecin.
@ast
Induction of cleavage in topoi ...... e and absence of camptothecin.
@en
type
label
Induction of cleavage in topoi ...... e and absence of camptothecin.
@ast
Induction of cleavage in topoi ...... e and absence of camptothecin.
@en
prefLabel
Induction of cleavage in topoi ...... e and absence of camptothecin.
@ast
Induction of cleavage in topoi ...... e and absence of camptothecin.
@en
P2093
P2860
P356
P1476
Induction of cleavage in topoi ...... e and absence of camptothecin.
@en
P2093
P2860
P304
P356
10.1093/NAR/21.22.5157
P407
P577
1993-11-01T00:00:00Z