Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription.
about
TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease miceTransforming growth factor-beta1 up-regulation of human alpha(1)(I) collagen is mediated by Sp1 and Smad2 transacting factors.Concerted perturbation observed in a hub network in Alzheimer's diseasePost-transcriptional regulation of amyloid precursor protein by microRNAs and RNA binding proteins.mTOR inhibition rescues osteopenia in mice with systemic sclerosis.WW domain-containing oxidoreductase in neuronal injury and neurological diseases.Tolfenamic acid reduces tau and CDK5 levels: implications for dementia and tauopathies.Interleukin17A Promotes Postoperative Cognitive Dysfunction by Triggering β-Amyloid Accumulation via the Transforming Growth Factor-β (TGFβ)/Smad Signaling PathwayAlzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme.Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease.Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and miceThe TGF-beta1/upstream stimulatory factor-regulated PAI-1 gene: potential involvement and a therapeutic target in Alzheimer's diseaseEpigenetics: a novel therapeutic approach for the treatment of Alzheimer's diseaseInfantile exposure to lead and late-age cognitive decline: relevance to AD.NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells.The beneficial role of vitamin D in Alzheimer's disease.Role of thiamine in Alzheimer's disease.Neuron-astroglial interactions in cell-fate commitment and maturation in the central nervous system.Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation.Specificity protein 1 and Smad-dependent regulation of human heme oxygenase-1 gene by transforming growth factor-beta1 in renal epithelial cells.S100B-induced microglial and neuronal IL-1 expression is mediated by cell type-specific transcription factors.Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta.TGF-beta1 modulates focal adhesion kinase expression in rat intestinal epithelial IEC-6 cells via stimulatory and inhibitory Smad binding elements.Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.Association between Polymorphisms of the AKT1 Gene Promoter and Risk of the Alzheimer's Disease in a Chinese Han Population with Type 2 Diabetes.Transcription factor Sp1 inhibition, memory, and cytokines in a mouse model of Alzheimer's disease.Co-localization and distribution of cerebral APP and SP1 and its relationship to amyloidogenesis.Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus.Tomoregulin-2 is found extensively in plaques in Alzheimer's disease brain.The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases.Mithramycin A Alleviates Cognitive Deficits and Reduces Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease.
P2860
Q30498066-E747EE32-FBED-425C-8054-BB89A510D7ECQ30541295-6558A703-7F43-43A4-A0D3-F5B0A1787CDEQ33805741-56CA613C-5582-43EB-A4CB-291149BB18F0Q34344867-9C7F6575-5B69-403C-9049-5370E7D83903Q34570186-16180982-B959-4B6A-9FAD-D390F9E09966Q34924612-14DCD14C-8B5A-455F-9927-92716F564715Q35067919-0482F3D9-E6A5-413D-BE69-57F032517625Q35264520-BF9A4CA7-820B-498F-804A-970EC0DB2782Q35824163-1883291A-DE9C-4127-B847-4F6AC23B0100Q36016766-7374EFD7-6917-4D2D-8E5F-C06C32EDE2FBQ36483870-2E1577EC-0D8F-41E7-883C-6A3676599401Q36603312-2C4842DF-9852-4284-B0BA-C3157E0E3511Q36626366-5336E743-1D33-4005-B97D-160D3AC441C7Q36956287-9BB3A375-C297-48E5-B006-848F0560D7A5Q37395859-6B50E164-43BD-416F-9C5B-EB9107EBDDB3Q37687793-0E1E5152-B19E-45B8-884B-C9EB4F296A2AQ37971804-2B41F089-C559-42CA-87D1-C739178C555AQ37973263-C7C17574-BA7D-4476-ACE4-C4D33A7C8F20Q38012043-4F6926DA-D8A1-4E9A-8D2B-272A84AF7726Q38260767-5418FB2C-9088-462B-B27B-DE099F88ECFAQ38300840-5D5D0951-3143-4E02-85B4-991EC6A60D6AQ38331759-71AFE080-463B-40DE-AD90-8F9B4093091EQ39881635-6C5C10C0-7BF7-477E-B273-5D1ED03A2CA5Q39908378-64669428-D7EE-4EC4-BFE4-0157DE827631Q41328860-7852AC1F-E993-46D5-8429-40B44F4D224FQ41583234-5AA1A69E-DC58-457B-B11A-6A60A8408F66Q43106647-D311171F-CB09-4D86-8EB6-92B4A3A6ECDEQ46707342-D9B72269-6EFD-4F3C-98E5-F81687733D14Q47550300-119DA9E2-3D76-497E-A5D9-293A0A9E547CQ48485666-511D2A48-9050-4AE3-9624-3B8BA1FD2B94Q50306250-C9721D99-6006-4CD5-A2D7-AF7A68339D1DQ50520724-55B3BCF0-0B13-48F1-AF25-D7028C69B250
P2860
Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Sp1 and Smad transcription fac ...... or protein gene transcription.
@en
type
label
Sp1 and Smad transcription fac ...... or protein gene transcription.
@en
prefLabel
Sp1 and Smad transcription fac ...... or protein gene transcription.
@en
P2093
P2860
P50
P356
P1433
P1476
Sp1 and Smad transcription fac ...... sor protein gene transcription
@en
P2093
Cecilia Gabriel
Laurent Plawinski
Nathalie Lebeurrier
Yannick Hommet
P2860
P304
P356
10.1042/BJ20040682
P407
P577
2004-10-01T00:00:00Z