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Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradationSurvivin monomer plays an essential role in apoptosis regulationThreonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitroE-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced beta-catenin-Tcf/Lef-dependent transcriptionNovel therapeutic targets for pancreatic cancerHuman inhibitor of apoptosis proteins: why XIAP is the black sheep of the familyLocalization and upregulation of survivin in cancer health disparities: a clinical perspectiveSurvivin: A molecular biomarker in cancerSurvivin and angiotensin-converting enzyme polymorphisms with risk of colorectal cancer: a systematic review and meta-analysisAn indirubin derivative, indirubin-3'-monoxime suppresses oral cancer tumorigenesis through the downregulation of survivinSurvivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasionSip18 hydrophilin prevents yeast cell death during desiccation stress.Targeting survivin in cancer therapyMitochondria and FOXO3: breath or dieA novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activityLoss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinomaTransforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cellsATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagyIAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells.p42MAPK-mediated phosphorylation of xEIAP/XLX in Xenopus cytostatic factor-arrested egg extracts.Carboxyfullerenes localize within mitochondria and prevent the UVB-induced intrinsic apoptotic pathway.YM155 Down-Regulates Survivin and Induces P53 Up-Regulated Modulator of Apoptosis (PUMA)-Dependent in Oral Squamous Cell Carcinoma Cells.Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.IAP regulation of metastasis.Identification of a novel TGFβ/PKA signaling transduceome in mediating control of cell survival and metastasis in colon cancer.Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cellsDifferential requirements for survivin in hematopoietic cell development.Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.X-linked inhibitor of apoptosis protein inhibits apoptosis in inflammatory breast cancer cells with acquired resistance to an ErbB1/2 tyrosine kinase inhibitor.Down-regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy.Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcriptionYM155 induces EGFR suppression in pancreatic cancer cells.Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells.The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancerDegradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex.Critical role of a survivin/TGF-β/mTORC1 axis in IGF-I-mediated growth of prostate epithelial cellsPrognostic and clinicopathological significance of survivin in colorectal cancer: a meta-analysisPreclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1.YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells.Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
An IAP-IAP complex inhibits apoptosis.
@en
type
label
An IAP-IAP complex inhibits apoptosis.
@en
prefLabel
An IAP-IAP complex inhibits apoptosis.
@en
P2093
P356
P1476
An IAP-IAP complex inhibits apoptosis.
@en
P2093
Casey E Wilford
Dario C Altieri
Guy S Salvesen
Hiroyouki Marusawa
John C Reed
Kate Welsh
Kazuya Okada
Robert Armstrong
P304
34087-34090
P356
10.1074/JBC.C400236200
P407
P577
2004-06-24T00:00:00Z