YM155 induces EGFR suppression in pancreatic cancer cells. - Wikidata - wikimedia - TriplyDB

YM155 induces EGFR suppression in pancreatic cancer cells.

YM155 induces EGFR suppression in pancreatic cancer cells.

http://www.wikidata.org/entity/Q34313903

about

Survivin: a unique target for tumor therapy Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma Cellular inhibitor of apoptosis protein 1 (cIAP1) stability contributes to YM155 resistance in human gastric cancer cells.Targeting survivin in cancer: novel drug development approaches.Small molecule inhibitor YM155-mediated activation of death receptor 5 is crucial for chemotherapy-induced apoptosis in pancreatic carcinoma.AML sensitivity to YM155 is modulated through AKT and Mcl-1.Drug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancer Survivin inhibitor YM155 suppresses gastric cancer xenograft growth in mice without affecting normal tissues Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-κB pathway Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil.YM155 induces apoptosis through downregulation of specificity protein 1 and myeloid cell leukemia-1 in human oral cancer cell lines.YM155 reverses rapamycin resistance in renal cancer by decreasing survivin.YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells.Inhibitor of Apoptosis Proteins: Promising Targets for Cancer Therapy.Modulation of P1 and EGF expression by Baicalin.Drug-perturbation-based stratification of blood cancer.Inhibitors of apoptosis: clinical implications in cancer.YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1.Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cells

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YM155 induces EGFR suppression in pancreatic cancer cells.

http://www.wikidata.org/entity/Q34313903

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

YM155 induces EGFR suppression in pancreatic cancer cells.

@ast

YM155 induces EGFR suppression in pancreatic cancer cells.

@en

YM155 induces EGFR suppression in pancreatic cancer cells.

@nl

type

label

YM155 induces EGFR suppression in pancreatic cancer cells.

@ast

YM155 induces EGFR suppression in pancreatic cancer cells.

@en

YM155 induces EGFR suppression in pancreatic cancer cells.

@nl

prefLabel

YM155 induces EGFR suppression in pancreatic cancer cells.

@ast

YM155 induces EGFR suppression in pancreatic cancer cells.

@en

YM155 induces EGFR suppression in pancreatic cancer cells.

@nl

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JOURNAL.PONE.0038625

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YM155 induces EGFR suppression in pancreatic cancer cells.

@en

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Dok Hyun Yoon

http://www.w3.org/2001/XMLSchema#string

Jae-Lyun Lee

http://www.w3.org/2001/XMLSchema#string

Jae-Sik Shin

http://www.w3.org/2001/XMLSchema#string

Jai-Hee Moon

http://www.w3.org/2001/XMLSchema#string

Jung Shin Lee

http://www.w3.org/2001/XMLSchema#string

Kyung-Ah Jung

http://www.w3.org/2001/XMLSchema#string

Min-Hee Ryu

http://www.w3.org/2001/XMLSchema#string

Seung-Mi Kim

http://www.w3.org/2001/XMLSchema#string

Soo-Jin Yang

http://www.w3.org/2001/XMLSchema#string

Tae Won Kim

http://www.w3.org/2001/XMLSchema#string

P2860

Survivin: a protein with dual roles in mitosis and apoptosis

EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2.

Understanding resistance to EGFR inhibitors-impact on future treatment strategies

EGFR signaling and drug discovery.

Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

Epidermal growth factor receptor-targeted therapy for pancreatic cancer.

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10.1371/JOURNAL.PONE.0038625

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