RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposi's sarcoma-associated herpesvirus by the lytic switch protein RTA
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Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cellsIdentification of direct transcriptional targets of the Kaposi's sarcoma-associated herpesvirus Rta lytic switch protein by conditional nuclear localizationHost and viral proteins in the virion of Kaposi's sarcoma-associated herpesvirus.Binding of RBP-Jkappa (CSL) protein to the promoter of the Kaposi's sarcoma-associated herpesvirus ORF47 (gL) gene is a critical but not sufficient determinant of transactivation by ORF50 protein.Activation of the Kaposi's sarcoma-associated herpesvirus major latency locus by the lytic switch protein RTA (ORF50).Kaposi's sarcoma-associated herpesvirus K-bZIP represses gene transcription via SUMO modification.Upregulation of cellular Bcl-2 by the KSHV encoded RTA promotes virion productionThe RBP-Jκ binding sites within the RTA promoter regulate KSHV latent infection and cell proliferation.Abortive lytic reactivation of KSHV in CBF1/CSL deficient human B cell lines.The single RBP-Jkappa site within the LANA promoter is crucial for establishing Kaposi's sarcoma-associated herpesvirus latency during primary infectionMolecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesisModulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Replication and transcription activator (RTA) of murine gammaherpesvirus 68 binds to an RTA-responsive element and activates the expression of ORF18Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induction by hypoxia and hypoxia-inducible factors.Cooperation between viral interferon regulatory factor 4 and RTA to activate a subset of Kaposi's sarcoma-associated herpesvirus lytic promotersKaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta lytic switch protein functions as a tetramerEssential role of RBP-Jkappa in activation of the K8 delayed-early promoter of Kaposi's sarcoma-associated herpesvirus by ORF50/RTA.An alternative Kaposi's sarcoma-associated herpesvirus replication program triggered by host cell apoptosis.Promoter- and cell-specific transcriptional transactivation by the Kaposi's sarcoma-associated herpesvirus ORF57/Mta protein.Notch and Wnt signaling: mimicry and manipulation by gamma herpesviruses.Genome-wide identification of binding sites for Kaposi's sarcoma-associated herpesvirus lytic switch protein, RTA.Kaposi's Sarcoma-Associated Herpesvirus Subversion of the Anti-Inflammatory Response in Human Skin Cells Reveals Correlates of Latency and Disease Pathogenesis.KSHV Rta Promoter Specification and Viral Reactivation.Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?Role of Notch signal transduction in Kaposi's sarcoma-associated herpesvirus gene expressionActivation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTAKaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling.Wide-scale use of Notch signaling factor CSL/RBP-Jkappa in RTA-mediated activation of Kaposi's sarcoma-associated herpesvirus lytic genesKaposi's Sarcoma-associated herpesvirus lytic switch protein stimulates DNA binding of RBP-Jk/CSL to activate the Notch pathway.Hijacking GPCRs by viral pathogens and tumor.Kaposi's sarcoma-associated herpesvirus Rta tetramers make high-affinity interactions with repetitive DNA elements in the Mta promoter to stimulate DNA binding of RBP-Jk/CSL.Quantitative analysis of the bidirectional viral G-protein-coupled receptor and lytic latency-associated nuclear antigen promoter of Kaposi's sarcoma-associated herpesvirus.Multiple defects, including premature apoptosis, prevent Kaposi's sarcoma-associated herpesvirus replication in murine cells.Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: maintenance of tight latency with efficient reactivation upon induction.Transcripts encoding K12, v-FLIP, v-cyclin, and the microRNA cluster of Kaposi's sarcoma-associated herpesvirus originate from a common promoter.The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells.Identification and characterization of a new Kaposi's sarcoma-associated herpesvirus replication and transcription activator (RTA)-responsive element involved in RTA-mediated transactivation.Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators.Direct interactions of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta protein with the cellular protein octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivatiThe transcriptional repressor K-RBP modulates RTA-mediated transactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus.
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P2860
RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposi's sarcoma-associated herpesvirus by the lytic switch protein RTA
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
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@zh-cn
name
RBP-J (CSL) is essential for a ...... y the lytic switch protein RTA
@en
type
label
RBP-J (CSL) is essential for a ...... y the lytic switch protein RTA
@en
prefLabel
RBP-J (CSL) is essential for a ...... y the lytic switch protein RTA
@en
P2860
P1433
P1476
RBP-J (CSL) is essential for a ...... y the lytic switch protein RTA
@en
P2093
Yuying Liang
P2860
P304
P356
10.1128/JVI.78.13.6818-6826.2004
P407
P577
2004-07-01T00:00:00Z