Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
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TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cellsFOXD3 regulates migration properties and Rnd3 expression in melanoma cellsSynergistic inhibition of human melanoma proliferation by combination treatment with B-Raf inhibitor BAY43-9006 and mTOR inhibitor RapamycinThe Complexity of the ERK/MAP-Kinase Pathway and the Treatment of Melanoma Skin CancerInactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.Evaluation of molecular markers of mesenchymal phenotype in melanoma.B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organizationRnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensionsMMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf.BRAF(V600E) melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity.Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032.Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness.Global analysis of BRAFV600E target genes in human melanocytes identifies matrix metalloproteinase-1 as a critical mediator of melanoma growthMolecular bases of cutaneous and uveal melanomas.Expression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice.Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase.CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity.RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13.Influence of single nucleotide polymorphisms in the MMP1 promoter region on cutaneous melanoma progression.Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway.p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasionBRAF(E600) in benign and malignant human tumours.Understanding signaling cascades in melanomaBeneficial role of overexpression of TFPI-2 on tumour progression in human small cell lung cancer.Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis.Plasma matrix metalloproteinase 1 improves the detection and survival prediction of esophageal squamous cell carcinoma.Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression.Gab2-mediated signaling promotes melanoma metastasis.TFPI-2 silencing increases tumour progression and promotes metalloproteinase 1 and 3 induction through tumour-stromal cell interactions.The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cellsDifferential mechanisms of tumor progression in clones from a single heterogeneous human melanoma.Genetics and genomics of melanoma.A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis.Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032.Emerging molecular targets in melanoma invasion and metastasis.BRAF mutation testing algorithm for vemurafenib treatment in melanoma: recommendations from an expert panel.Metastasis review: from bench to bedside.Induction of heparanase-1 expression by mutant B-Raf kinase: role of GA binding protein in heparanase-1 promoter activation.Fisetin suppresses ADAM9 expression and inhibits invasion of glioma cancer cells through increased phosphorylation of ERK1/2.
P2860
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P2860
Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Overexpression of collagenase ...... blast growth factor signaling.
@en
type
label
Overexpression of collagenase ...... blast growth factor signaling.
@en
prefLabel
Overexpression of collagenase ...... blast growth factor signaling.
@en
P2093
P2860
P356
P1476
Overexpression of collagenase ...... blast growth factor signaling.
@en
P2093
Channing J Der
Colby A Wyatt
Constance E Brinckerhoff
Janiel M Shields
Jonathan T Huntington
Ulrike Benbow
P2860
P304
33168-33176
P356
10.1074/JBC.M405102200
P407
P577
2004-06-07T00:00:00Z