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Protein binding and signaling properties of RIN1 suggest a unique effector functionThe RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activationMeaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsMapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cellsThe RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformationAssociation of yeast adenylyl cyclase with cyclase-associated protein CAP forms a second Ras-binding site which mediates its Ras-dependent activationThe strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPasesActivation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffoldsThe solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding sitePhosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signalingInteraction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cellsIncreased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activationIdentification of neurofibromin mutants that exhibit allele specificity or increased Ras affinity resulting in suppression of activated ras allelesActivation of CD4 T cells by Raf-independent effectors of RasAutoregulation of the Raf-1 serine/threonine kinaseRab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by rasStructural basis for the interaction of Ras with RalGDSIdentification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1Ras-induced cellular events (review)Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domainInteractions of the amino acid residue at position 31 of the c-Ha-Ras protein with Raf-1 and RalGDSCysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-RasEffect of phosphorylation on activities of Rap1A to interact with Raf-1 and to suppress Ras-dependent Raf-1 activationInterleukin-1beta enhances bradykinin-induced phosphoinositide hydrolysis and Ca2+ mobilization in canine tracheal smooth-muscle cells: involvement of the Ras/Raf/mitogen-activated protein kinase (MAPK) kinase (MEK)/MAPK pathwayMitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathwayThe ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1Single-molecule force measurement via optical tweezers reveals different kinetic features of two BRaf mutants responsible for cardio-facial-cutaneous (CFC) syndromeEpidermal Growth Factor Receptor Cell Proliferation Signaling Pathways14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo.TC21 and Ras share indistinguishable transforming and differentiating activities.The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activationMammalian Raf-1 is activated by mutations that restore Raf signaling in DrosophilaPhosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.Structural determinants of Ras-Raf interaction analyzed in live cells.Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphataseThe Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation.The RASSF1A tumor suppressor activates Bax via MOAP-1.
P2860
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P2860
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Two distinct Raf domains mediate interaction with Ras
@ast
Two distinct Raf domains mediate interaction with Ras
@en
Two distinct Raf domains mediate interaction with Ras
@nl
type
label
Two distinct Raf domains mediate interaction with Ras
@ast
Two distinct Raf domains mediate interaction with Ras
@en
Two distinct Raf domains mediate interaction with Ras
@nl
prefLabel
Two distinct Raf domains mediate interaction with Ras
@ast
Two distinct Raf domains mediate interaction with Ras
@en
Two distinct Raf domains mediate interaction with Ras
@nl
P2093
P2860
P356
P1476
Two distinct Raf domains mediate interaction with Ras
@en
P2093
J K Drugan
R S Terrell
S Campbell-Burk
P2860
P304
P356
10.1074/JBC.270.17.9809
P407
P577
1995-04-28T00:00:00Z