IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.
about
von Willebrand factor type D domain mutant of SVS-1/SUSD2, vWD(m), induces apoptosis in HeLa cells.Luteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3.Heat shock proteins as emerging therapeutic targets.Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment.Natural products-prompted chemical biology: phenotypic screening and a new platform for target identification.Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small cell lung cancer.Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B.Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.Molecular modelling and docking studies on heat shock protein 90 (Hsp90) inhibitors.Pharmacophore-based virtual screening and docking studies on Hsp90 inhibitors.
P2860
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P2860
IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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2004年论文
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name
IC101 induces apoptosis by Akt ...... ction with Akt in L1210 cells.
@en
type
label
IC101 induces apoptosis by Akt ...... ction with Akt in L1210 cells.
@en
prefLabel
IC101 induces apoptosis by Akt ...... ction with Akt in L1210 cells.
@en
P2093
P356
P1476
IC101 induces apoptosis by Akt ...... action with Akt in L1210 cells
@en
P2093
Hironori Fujiwara
Masaaki Ishizuka
Mitsuhiro Ueno
Takashi Shinkawa
Toshiaki Isobe
Yasushi Ohizumi
P304
P356
10.1124/JPET.104.065979
P407
P50
P577
2004-05-25T00:00:00Z