Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid.
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MX2 is an interferon-induced inhibitor of HIV-1 infectionCyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cellsSpecific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factorFunctional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domainsInhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agentCPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 ReplicationGain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α SpecificityLv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationThe KT Jeang Retrovirology prize 2015: Paul BieniaszApparent effect of rabbit endogenous lentivirus type K acquisition on retrovirus restriction by lagomorph Trim5αsPrimate TRIM5 proteins form hexagonal nets on HIV-1 capsids.SIV replication in human cellsA specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.TRIM5 alpha drives SIVsmm evolution in rhesus macaques.The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection.Novel approaches to inhibiting HIV-1 replication.TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new speciesRetrovirus restriction by TRIM5alpha variants from Old World and New World primatesHsp70 interacts with the retroviral restriction factor TRIM5alpha and assists the folding of TRIM5alphaResidues in the murine leukemia virus capsid that differentially govern resistance to mouse Fv1 and human Ref1 restrictions.The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primatesSpecies-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restrictionAn envelope-determined, pH-independent endocytic route of viral entry determines the susceptibility of human immunodeficiency virus type 1 (HIV-1) and HIV-2 to Lv2 restriction.Retroviral restriction factor TRIM5alpha is a trimerInteraction of moloney murine leukemia virus capsid with Ubc9 and PIASy mediates SUMO-1 addition required early in infection.Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5αGenetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infectionThe hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms.Genetic Dissection of the Host Tropism of Human-Tropic Pathogens.Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restrictionEvolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection.Extreme genetic fragility of the HIV-1 capsid.Modulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms.The TRIM5{alpha} genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challengeThe TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infectionGenetic Studies of the beta-hairpin loop of Rous sarcoma virus capsid protein.A single amino acid of the human immunodeficiency virus type 2 capsid affects its replication in the presence of cynomolgus monkey and human TRIM5alphasControl of viral infectivity by tripartite motif proteins.
P2860
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P2860
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid.
@en
type
label
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid.
@en
prefLabel
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid.
@en
P2093
P2860
P1433
P1476
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid.
@en
P2093
Paul D Bieniasz
Simone Cowan
Theodora Hatziioannou
Uta K Von Schwedler
Wesley I Sundquist
P2860
P304
P356
10.1128/JVI.78.11.6005-6012.2004
P407
P577
2004-06-01T00:00:00Z