The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.
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A novel ubiquitin-binding protein ZNF216 functioning in muscle atrophyMuscle atrophy in transgenic mice expressing a human TSC1 transgeneThe initiation factor eIF3-f is a major target for atrogin1/MAFbx function in skeletal muscle atrophyCancer cachexia--pathophysiology and managementSkeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucinePeroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophyFed-state clamp stimulates cellular mechanisms of muscle protein anabolism and modulates glucose disposal in normal menExercise and health: can biotechnology confer similar benefits?Adiponectin resistance in skeletal muscle: pathophysiological implications in chronic heart failureIn Vivo Rodent Models of Skeletal Muscle Adaptation to Decreased UseLong live FOXO: unraveling the role of FOXO proteins in aging and longevityBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesConnecting Myokines and MetabolismFOXO transcription factors: key regulators of cellular quality controlAutophagy is essential to support skeletal muscle plasticity in response to endurance exerciseCellular and molecular mechanisms of muscle atrophyRole of autophagy in COPD skeletal muscle dysfunctionIL-6 and IGF-1 Signaling Within and Between Muscle and Bone: How Important is the mTOR Pathway for Bone Metabolism?Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategiesStatin-Induced Increases in Atrophy Gene Expression Occur Independently of Changes in PGC1α Protein and Mitochondrial ContentMuscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of duchenne muscular dystrophyLeptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob miceMetabolic benefits of resistance training and fast glycolytic skeletal muscle.Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia--can findings from animal models be translated to humans?Inflammatory Mechanisms Associated with Skeletal Muscle Sequelae after Stroke: Role of Physical ExerciseDisrupted autophagy undermines skeletal muscle adaptation and integrityFoxO1: a novel insight into its molecular mechanisms in the regulation of skeletal muscle differentiation and fiber type specificationmRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle massEmerging drugs for sarcopenia: age-related muscle wastingDistinct protein degradation profiles are induced by different disuse models of skeletal muscle atrophyBerberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesisSwimming exercise prevents fibrogenesis in chronic kidney disease by inhibiting the myofibroblast transdifferentiationGlucocorticoid-induced leucine zipper (GILZ) and long GILZ inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoidsInsulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiationInhibition of atrogin-1/MAFbx mediated MyoD proteolysis prevents skeletal muscle atrophy in vivoThe p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteinsReversal of muscle atrophy by Zhimu-Huangbai herb-pair via Akt/mTOR/FoxO3 signal pathway in streptozotocin-induced diabetic miceβ-Hydroxy β-methylbutyrate improves dexamethasone-induced muscle atrophy by modulating the muscle degradation pathway in SD ratRegulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated ratsPlasminogen activator inhibitor type 1 up-regulation is associated with skeletal muscle atrophy and associated fibrosis
P2860
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P2860
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The IGF-1/PI3K/Akt pathway pre ...... ng FOXO transcription factors.
@en
type
label
The IGF-1/PI3K/Akt pathway pre ...... ng FOXO transcription factors.
@en
prefLabel
The IGF-1/PI3K/Akt pathway pre ...... ng FOXO transcription factors.
@en
P2093
P1433
P1476
The IGF-1/PI3K/Akt pathway pre ...... ng FOXO transcription factors.
@en
P2093
Brian A Clarke
David J Glass
Doreen Drujan
Frank Panaro
George D Yancopoulos
Michael Gonzalez
Trevor N Stitt
William O Kline
Yekatarina Timofeyva
P304
P356
10.1016/S1097-2765(04)00211-4
P577
2004-05-01T00:00:00Z