Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
about
PUMA, a potent killer with or without p53Effects of IkappaBalpha and its mutants on NF-kappaB and p53 signaling pathways.Comparative proteomics analysis of cardiac muscle samples from pufferfish Takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis.Involvement of NF-kappaB activation in the apoptosis induced by extracellular adenosine in human hepatocellular carcinoma HepG2 cells.Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase.PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.NF-kappaB activation enhances cell death by antimitotic drugs in human prostate cancer cells.IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy.Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.The effect of bortezomib on expression of inflammatory cytokines and survival in a murine sepsis model induced by cecal ligation and puncture.Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity.Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities.TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation.NF-κB inhibition compromises cardiac fibroblast viability under hypoxia.Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicityIκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptorProteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesisSuberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells.Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.Proteasome inhibition as a therapeutic strategy for hematologic malignancies.Apoptin: specific killer of tumor cells?Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence.Proteasome inhibition as novel treatment strategy in leukaemia.IKK-β mediates hydrogen peroxide induced cell death through p85 S6K1Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma.Dual roles of NF-kappaB in cell survival and implications of NF-kappaB inhibitors in neuroprotective therapy.Reactivation of p53 by novel MDM2 inhibitors: implications for pancreatic cancer therapy.Loss of IKKbeta activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosisLeukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway.Bisindolylmaleimide alkaloid BMA-155Cl induces autophagy and apoptosis in human hepatocarcinoma HepG-2 cells through the NF-κB p65 pathwayNF-κB activation was involved in reactive oxygen species-mediated apoptosis and autophagy in 1-oxoeudesm-11(13)-eno-12,8α-lactone-treated human lung cancer cells.Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-kappaB signalling pathways in human pancreatic adenocarcinoma cells.Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis.Epstein-Barr virus latent membrane protein 1 represses p53-mediated DNA repair and transcriptional activity.Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor.Protein kinase C-dependent regulation of NAG-1/placental bone morphogenic protein/MIC-1 expression in LNCaP prostate carcinoma cells.Development of an inducible suicide gene system based on human caspase 8.Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response.Targeting nuclear factor-kappa B to overcome resistance to chemotherapy.
P2860
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P2860
Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
@en
type
label
Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
@en
prefLabel
Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
@en
P2093
P2860
P356
P1476
Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB
@en
P2093
Bailu Peng
Douglas B Evans
Guido M Sclabas
Hélène Pelicano
James L Abbruzzese
Jiangong Niu
Paul J Chiao
Peng Huang
Shuichi Fujioka
P2860
P304
27549-27559
P356
10.1074/JBC.M313435200
P407
P577
2004-04-21T00:00:00Z