The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
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Regulation of Bim in Health and DiseaseHistone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyEpigenetic regulation in human melanoma: past and futureSynergistic interactions between HDAC and sirtuin inhibitors in human leukemia cellsAberrant histone acetylation promotes mitochondrial respiratory suppression in the brain of alcoholic rats.Exposure to a histone deacetylase inhibitor has detrimental effects on human lymphocyte viability and function.Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions.The clinical development of histone deacetylase inhibitors as targeted anticancer drugs.Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategiesHistone deacetylase inhibitor sensitizes apoptosis-resistant melanomas to cytotoxic human T lymphocytes through regulation of TRAIL/DR5 pathway.HDAC inhibitor, valproic acid, induces p53-dependent radiosensitization of colon cancer cells.New insights into the treatment of multiple myeloma with histone deacetylase inhibitors.Histone Deacetylase Inhibitors: Advancing Therapeutic Strategies in Hematological and Solid Malignancies.Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimSCombination phenylbutyrate/gemcitabine therapy effectively inhibits in vitro and in vivo growth of NSCLC by intrinsic apoptotic pathwaysHistone deacetylase inhibitors in clinical studies as templates for new anticancer agents.Inhibition of mouse B16 melanoma by sodium butyrate correlated to tumor associated macrophages differentiation suppression.Lead Induces Apoptosis and Histone Hyperacetylation in Rat Cardiovascular Tissues.Proteasome inhibition blocks NF-κB and ERK1/2 pathways, restores antigen expression, and sensitizes resistant human melanoma to TCR-engineered CTLsActivation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis.A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells.Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling.Cutaneous T-cell lymphoma: 2016 update on diagnosis, risk-stratification, and management.Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate.Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3.Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824.Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras.Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect.Drugging the undruggable: transcription therapy for cancer.Combining cancer immunotherapy and targeted therapy.Melanoma epigenetics: novel mechanisms, markers, and medicines.Belinostat exerts antitumor cytotoxicity through the ubiquitin-proteasome pathway in lung squamous cell carcinomaInteractive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.Combination of palladium nanoparticles and tubastatin-A potentiates apoptosis in human breast cancer cells: a novel therapeutic approach for cancer.The effect of combined treatment with cisplatin and histone deacetylase inhibitors on HeLa cells.Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca2+ Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK.Overcoming Resistance of Human Non-Hodgkin's Lymphoma to CD19-CAR CTL Therapy by Celecoxib and Histone Deacetylase Inhibitors.The HDAC Inhibitor Quisinostat (JNJ-26481585) Supresses Hepatocellular Carcinoma alone and Synergistically in Combination with Sorafenib by G0/G1 phase arrest and Apoptosis induction
P2860
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P2860
The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The histone deacetylase inhibi ...... t apoptosis of melanoma cells.
@en
type
label
The histone deacetylase inhibi ...... t apoptosis of melanoma cells.
@en
prefLabel
The histone deacetylase inhibi ...... t apoptosis of melanoma cells.
@en
P2093
P1476
The histone deacetylase inhibi ...... nt apoptosis of melanoma cells
@en
P2093
Jodie M Borrow
Peter Hersey
Susan K Gillespie
P304
P577
2004-04-01T00:00:00Z