Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
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Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancersCaveolin-1, a stress-related oncotarget, in drug resistanceNitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status.Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation.Caveolin-1 is required for kinase suppressor of Ras 1 (KSR1)-mediated extracellular signal-regulated kinase 1/2 activation, H-RasV12-induced senescence, and transformationAn absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease.Cellular prion protein and caveolin-1 interaction in a neuronal cell line precedes Fyn/Erk 1/2 signal transduction.Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblastsCaveolin-1 in oncogenic transformation, cancer, and metastasis.Cav1 suppresses tumor growth and metastasis in a murine model of cutaneous SCC through modulation of MAPK/AP-1 activationFunctional proteomics characterization of residual breast cancer after neoadjuvant systemic chemotherapy.Li Fraumeni syndrome, cancer and senescence: a new hypothesis.Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepubertyCaveolin-1: an ambiguous partner in cell signalling and cancer.Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders.MMTV promoter-regulated caveolin-1 overexpression yields defective parenchymal epithelia in multiple exocrine organs of transgenic mice.Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib.Caveolins in rhabdomyosarcomaMolecular genetics in glaucoma.The role of caveolin-1 in human breast cancer.Down-regulation of the cavin family proteins in breast cancer.A role for polypyrimidine tract binding protein in the establishment of focal adhesions.Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells.Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells.Metastatic potential of mouse Lewis lung cancer cells is regulated via ganglioside GM1 by modulating the matrix metalloprotease-9 localization in lipid rafts.Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine.Biphasic Regulation of Caveolin-1 Gene Expression by Fluoxetine in Astrocytes: Opposite Effects of PI3K/AKT and MAPK/ERK Signaling Pathways on c-fos.Oncogenomics of c-Myc transgenic mice reveal novel regulators of extracellular signaling, angiogenesis and invasion with clinical significance for human lung adenocarcinoma.Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence.Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice.Deficiency of caveolin-1 in Apc(min/+) mice promotes colorectal tumorigenesis.Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of caveolin-1.Global gene expression profiling and tissue microarray reveal novel candidate genes and down-regulation of the tumor suppressor gene CAV1 in sporadic vestibular schwannomas.Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1
P2860
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P2860
Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Combined loss of INK4a and cav ...... y epithelial cell hyperplasia.
@en
type
label
Combined loss of INK4a and cav ...... y epithelial cell hyperplasia.
@en
prefLabel
Combined loss of INK4a and cav ...... y epithelial cell hyperplasia.
@en
P2093
P2860
P356
P1476
Combined loss of INK4a and cav ...... y epithelial cell hyperplasia.
@en
P2093
Alex W Cohen
Babak Razani
Hyangkyu Lee
Michelle W-C Cheung
Philipp E Scherer
Puneeth Iyengar
Richard G Pestell
Terence M Williams
P2860
P304
24745-24756
P356
10.1074/JBC.M402064200
P407
P577
2004-03-25T00:00:00Z