Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts.
about
Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancersIntegrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cellsThe role of Src in solid tumorsRegulation of mitochondrial functions by protein phosphorylation and dephosphorylationAndrogen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinasesSRC: marker or actor in prostate cancer aggressivenessCrystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound stateRadotinib Induces Apoptosis of CD11b+ Cells Differentiated from Acute Myeloid Leukemia CellsA randomized phase II study of cediranib alone versus cediranib in combination with dasatinib in docetaxel resistant, castration resistant prostate cancer patients.Saracatinib as a metastasis inhibitor in metastatic castration-resistant prostate cancer: A University of Chicago Phase 2 Consortium and DOD/PCF Prostate Cancer Clinical Trials Consortium Study.Kinase modulation of androgen receptor signaling: implications for prostate cancerC-Src-mediated phosphorylation of δ-catenin increases its protein stability and the ability of inducing nuclear distribution of β-catenin.LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer.Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cellsShedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration.C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha.Activation of Lyn tyrosine kinase through decreased membrane cholesterol levels during a change in its membrane distribution upon cell detachment.Breast cancer patients' clinical outcome measures are associated with Src kinase family member expression.Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor.Differential transformation capacity of Src family kinases during the initiation of prostate cancer.Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy.Gene expression profiling analysis of castration-resistant prostate cancerYes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells.The Src kinase Lyn is required for CCR5 signaling in response to MIP-1beta and R5 HIV-1 gp120 in human macrophages.Src family kinases differentially influence glioma growth and motilityFunctions of the Lyn tyrosine kinase in health and diseaseSignaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.Nonreceptor tyrosine kinases in prostate cancer.Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma.The diverse functions of Src family kinases in macrophages.Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis.An arrestin-dependent multi-kinase signaling complex mediates MIP-1beta/CCL4 signaling and chemotaxis of primary human macrophages.Src controls castration recurrence of CWR22 prostate cancer xenografts.Dasatinib combined with docetaxel for castration-resistant prostate cancer: results from a phase 1-2 study.Signalling pathways in prostate carcinogenesis: potentials for molecular-targeted therapy.Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis.Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation.Targeting tyrosine kinases and autophagy in prostate cancer.Steps in prostate cancer progression that lead to bone metastasis
P2860
Q24294953-EE3BC11F-52D8-4492-946F-5D62EC478C69Q24304138-637E4553-025B-4BBA-9B72-87CBE87EF1F7Q24616659-0EED6D17-682C-4778-99AD-124A544F4F5BQ26752880-26F36456-110B-4BFF-9AC7-ACDFCAD0F014Q26866135-99C7F9DD-46B6-4A1C-B78C-B6A0FB530C76Q27012541-2B90F28D-2BE6-4206-9772-EFEB0246C6F8Q27652762-73AD8F7D-CE26-4D98-9C3B-BF7BD6E1E8D1Q28548235-CEFA2006-22C4-42ED-81F8-D010156DC894Q33415009-9E192AB0-C3A1-48CF-A99D-44F831551CF6Q33426973-CB7D7C7E-9E2F-497E-B1C0-0C53A7C9B8B0Q33757289-7B4FB031-FD5B-4333-99B7-8DC372156ED8Q33817799-50DCC7FD-3A52-4548-990E-27781B6F3650Q33848195-C248AC0C-43D8-4C55-A3AC-DF58EDD3BD8AQ33851800-D784C4DF-1E2C-4388-8A3A-7B7BE479CB43Q33958982-92E23491-2B85-41C1-8176-F5270EE30784Q33966470-5E916384-9AEF-442E-8DC5-346ED4E0B2BCQ34111744-5DBA221F-66EE-4B64-8C79-A380499794D0Q34248998-36335F96-F9EA-44D2-9D7F-04007F32F6FEQ34253693-CA3F75AA-4D66-4CCC-AC48-83BBAF6E66EEQ34595342-80A95867-74A0-4E08-A2D5-2FD47D02D19BQ34835580-C7E95112-12DB-4340-9E4A-2C770DFB8E60Q34926222-593567B6-C381-4847-A8BA-8A9B2EA338D5Q35014196-01C6E6AE-D7BB-4870-90EF-6E840DC8EA83Q35832949-D10C72BC-431C-4312-A890-41A9A5178B8EQ35849903-56AF0F72-BF9B-43F1-A1B9-6193184E9F38Q36218089-B7CDE5A5-3185-47F9-8832-A7F1646FD83DQ36299576-CFDD0974-DCA7-4F17-87EE-4B92DD677678Q36644832-A5E4DC56-E378-4F9E-AFF8-583D699EC9E5Q36759212-ED883068-E810-4CA9-8B4A-06DD88D67026Q36916923-99FF1225-0199-4D5C-A189-A13A9F36FB58Q37175318-D425E842-4DAD-4DB7-B2A1-8B1D71CF1376Q37287442-AC585D63-2D90-4E6D-8C59-5E07F5F0C7A6Q37362947-A2773E02-8B87-4857-BC67-1B0EE0523D41Q37481145-6B9ECE06-4E18-4064-BC9C-54DE527F4B88Q37502039-DD63BFB1-1651-45FB-9604-AC9D9280CEC4Q37575815-09C096D8-6966-43FF-BB5C-D08A0749F858Q37597360-3B1729C1-9F37-43F1-81E3-942DB1301701Q37644427-54460D01-E5B2-417A-9623-618154CE32B6Q37847052-D33228BA-92D8-4C3D-A048-C2D8A66354DFQ37848782-26C08E83-578E-459F-8A02-9AFC0948ECE2
P2860
Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Lyn is a target gene for prost ...... ion of human tumor xenografts.
@en
type
label
Lyn is a target gene for prost ...... ion of human tumor xenografts.
@en
prefLabel
Lyn is a target gene for prost ...... ion of human tumor xenografts.
@en
P2093
P1433
P1476
Lyn is a target gene for prost ...... ion of human tumor xenografts.
@en
P2093
Eli Pikarsky
Hadas Reuveni
Hila Rubin
Ilan Stein
Irina Weinstein
Marc Wygoda
Mirela Goldenberg-Furmanov
Shafika Kasem
Shmuel A Ben-Sasson
P304
P356
10.1158/0008-5472.CAN-03-2420
P407
P577
2004-02-01T00:00:00Z