Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. - Wikidata - wikimedia - TriplyDB

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

http://www.wikidata.org/entity/Q40602668

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Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors.ECHS1 interacts with STAT3 and negatively regulates STAT3 signaling Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein Cancer immunoediting from immune surveillance to immune escape Response rate of fibrosarcoma cells to cytotoxic drugs on the expression level correlates to the therapeutic response rate of fibrosarcomas and is mediated by regulation of apoptotic pathways Immunologic aspect of ovarian cancer and p53 as tumor antigen.Targeting microRNAs as key modulators of tumor immune response The emerging role of immunotherapy in head and neck squamous cell carcinoma (HNSCC): anti-tumor immunity and clinical applications Tumor-intrinsic oncogene pathways mediating immune avoidance Regulation of Natural Killer Cell Function by STAT3 Innate Immunity and Inflammation Post-Stroke: An α7-Nicotinic Agonist Perspective Paving the Road to Tumor Development and Spreading: Myeloid-Derived Suppressor Cells are Ruling the Fate The Role of the Transcriptional Regulation of Stromal Cells in Chronic Inflammation Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment The gastrointestinal tumor microenvironment Peptide Vaccine Therapy in Colorectal Cancer Vagus nerve stimulation: from epilepsy to the cholinergic anti-inflammatory pathway Diversification of dendritic cell subsets: Emerging roles for STAT proteins An immunologic portrait of cancer IL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammation The tumor microenvironment in esophageal cancer Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice Myeloid-derived cells are key targets of tumor immunotherapy Pathological mobilization and activities of dendritic cells in tumor-bearing hosts: challenges and opportunities for immunotherapy of cancer Coordinated regulation of myeloid cells by tumours Necdin, a negative growth regulator, is a novel STAT3 target gene down-regulated in human cancer Dihydroartemisinin as a Putative STAT3 Inhibitor, Suppresses the Growth of Head and Neck Squamous Cell Carcinoma by Targeting Jak2/STAT3 Signaling STATs in cancer inflammation and immunity: a leading role for STAT3 IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer Immunosuppressive networks in the tumour environment and their therapeutic relevance Immunosuppressive strategies that are mediated by tumor cells The SH3BGR/STAT3 Pathway Regulates Cell Migration and Angiogenesis Induced by a Gammaherpesvirus MicroRNA.Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth Interface of signal transduction inhibition and immunotherapy in melanoma.Tumor masses support naive T cell infiltration, activation, and differentiation into effectors M-HIFU inhibits tumor growth, suppresses STAT3 activity and enhances tumor specific immunity in a transplant tumor model of prostate cancer A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells

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P2860

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

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Dmitry Gabrilovich

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Domenico Coppola

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Drew Pardoll

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Guilian Niu

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Hua Yu

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Kenneth Shain

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Lyudmila Burdelya

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Marcin Kortylewski

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Raka Bhattacharya

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Richard Heller

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10.1038/NM976

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14702634

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