Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.
about
Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaksIdentification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase.Molecular and Cellular Effects of Hydrogen Peroxide on Human Lung Cancer Cells: Potential Therapeutic ImplicationsOxidative stress and replication-independent DNA breakage induced by arsenic in Saccharomyces cerevisiaeMitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage.Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutationTopoisomerase I requirement for death receptor-induced apoptotic nuclear fission.Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction.Estimation of lipid peroxidation induced by hydrogen peroxide in cultured human lymphocytes.Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.Oxidative stress and programmed cell death in yeast.Protective effect of ascorbic acid against oxidative damage induced by hydrogen peroxide in cultured human peripheral blood lymphocytesSusceptibility to bystander DNA damage is influenced by replication and transcriptional activity.Iron chelators with topoisomerase-inhibitory activity and their anticancer applications.DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.Tyrosyl-DNA phosphodiesterase as a target for anticancer therapyUltraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes.Facile and quantitative electrochemical detection of yeast cell apoptosis.The Top1 paradox: Friend and foe of the eukaryotic genome.Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide.The mouse mismatch repair protein, MSH3, is a nucleoplasmic protein that aggregates into denser nuclear bodies under conditions of stress.A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.A hydrogen peroxide detoxification system in the nucleus of wheat seed cells: protection or signaling role?Vitamin C prevents DNA damage induced by renovascular hypertension in multiple organs of Wistar rats.Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis.DNA-damaging effects of dental bleaching agents.Synergistic enhancement of topotecan-induced cell death by ascorbic acid in human breast MCF-7 tumor cells.Hydrogen peroxide generation from hydrated protein drink mixes.Effect of bleaching agent extracts on murine macrophages.DNA damage in the oligodendrocyte lineage and its role in brain aging.Cytogenetic damage induced by mouthrinses formulations in vivo and in vitro.PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin
P2860
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P2860
Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.
@en
type
label
Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.
@en
prefLabel
Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.
@en
P2093
P2860
P356
P1476
Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death
@en
P2093
Angela A Liu
Leroy F Liu
Shyamal D Desai
P2860
P304
14587-14594
P356
10.1074/JBC.M311370200
P407
P577
2003-12-19T00:00:00Z