iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
about
Cellular and molecular regulation of innate inflammatory responsesNonspecific DNA Binding of cGAS N Terminus Promotes cGAS Activation.Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.USP13 negatively regulates antiviral responses by deubiquitinating STINGMultifaceted roles of TRIM38 in innate immune and inflammatory responses.The Emerging Roles of STING in Bacterial Infections.cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.Post-translational Control of Intracellular Pathogen Sensing Pathways.Innate recognition of microbial-derived signals in immunity and inflammation.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.SPI-2/CrmA inhibits IFN-β induction by targeting TBK1/IKKε.Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses.TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF-TBK1 Interaction.p38 inhibition provides anti-DNA virus immunity by regulation of USP21 phosphorylation and STING activation.No TRIFling Matter on STING.PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation.TRIM29 promotes DNA virus infections by inhibiting innate immune response.iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA.Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response.SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes.iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.Delicate regulation of the cGAS-MITA-mediated innate immune response.iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complexThe Solute Carrier Transporter SLC15A3 Participates in Antiviral Innate Immune Responses against Herpes Simplex Virus-1SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITAHerpes Simplex Virus 1 γ34.5 Protein Inhibits STING Activation That Restricts Viral ReplicationInsights into the pathogenesis of herpes simplex encephalitis from mouse modelsZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune responseiRhom2 loss alleviates renal injury in long-term PM2.5-exposed mice by suppression of inflammation and oxidative stress
P2860
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P2860
iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
iRhom2 is essential for innate ...... tability of the adaptor STING.
@en
type
label
iRhom2 is essential for innate ...... tability of the adaptor STING.
@en
prefLabel
iRhom2 is essential for innate ...... tability of the adaptor STING.
@en
P2093
P2860
P356
P1433
P1476
iRhom2 is essential for innate ...... tability of the adaptor STING.
@en
P2093
Hong-Bing Shu
Wei-Wei Luo
P2860
P304
P356
10.1038/NI.3510
P407
P577
2016-07-18T00:00:00Z